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Items: 11

1.

Amikacin

A broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically locking 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. [from NCI]

MedGen UID:
1863
Concept ID:
C0002499
Antibiotic; Organic Chemical
2.

Central

Applies to an abnormality that is located close to the median plane or midline of the body or of the referenced structure. [from HPO]

MedGen UID:
59958
Concept ID:
C0205099
Spatial Concept
3.

Moraxellaceae Infections

Infections with bacteria of the family MORAXELLACEAE. [from MeSH]

MedGen UID:
219877
Concept ID:
C1258225
Disease or Syndrome
4.

Antimicrobial substance

Any substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause infection and disease). [from NCI_NCI-GLOSS]

MedGen UID:
209727
Concept ID:
C1136254
Pharmacologic Substance
5.

Disease due to Gram-negative bacteria

Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method. [from MeSH]

MedGen UID:
88406
Concept ID:
C0085423
Disease or Syndrome
6.

Bacterial Infections

Bacteria are living things that have only one cell. Under a microscope, they look like balls, rods, or spirals. They are so small that a line of 1,000 could fit across a pencil eraser. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. Bacteria are also used in making healthy foods like yogurt and cheese. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Antibiotics are the usual treatment. When you take antibiotics, follow the directions carefully. Each time you take antibiotics, you increase the chances that bacteria in your body will learn to resist them causing antibiotic resistance. Later, you could get or spread an infection that those antibiotics cannot cure. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
14012
Concept ID:
C0004623
Disease or Syndrome
7.

Kanamycin

Antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components. [from MeSH]

MedGen UID:
7193
Concept ID:
C0022487
Antibiotic; Organic Chemical
8.

Bacterial Infections and Mycoses

Infections caused by bacteria and fungi, general, specified, or unspecified. [from MeSH]

MedGen UID:
2161
Concept ID:
C0004615
Disease or Syndrome
9.

Acinetobacter Infections

Infections with bacteria of the genus ACINETOBACTER. [from MeSH]

MedGen UID:
1299
Concept ID:
C0001139
Disease or Syndrome
10.

Anti-Infective Agents

A pharmacological agent that can kill or prevent the reproduction of infectious organisms. [from NCI]

MedGen UID:
324
Concept ID:
C0003204
Pharmacologic Substance
11.

Aminoglycosides

Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS. [from MeSH]

MedGen UID:
257
Concept ID:
C0002556
Organic Chemical; Pharmacologic Substance
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