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Disorder of cardiovascular system

MedGen UID:
Concept ID:
Disease or Syndrome
Synonyms: Cardiovascular disease; Cardiovascular Disease Risk Factor (Angiotensin Converting Enzyme (ACE)); Cardiovascular Disease Risk Factor (Angiotensin II Receptor, Type 1); Cardiovascular Disease Risk Factor (Angiotensinogen); Cardiovascular Disease Risk Factor (Apolipoprotein E)
SNOMED CT: Disorder of cardiovascular system (49601007); CVD - cardiovascular disease (49601007); CVS disease - cardiovascular system disease (49601007); Cardiovascular system disease (49601007); Cardiovascular disorder (49601007); Cardiovascular disease (49601007)
Gene (location): ACE (17q23.3)


A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines


Ashley EA, Hershberger RE, Caleshu C, Ellinor PT, Garcia JG, Herrington DM, Ho CY, Johnson JA, Kittner SJ, Macrae CA, Mudd-Martin G, Rader DJ, Roden DM, Scholes D, Sellke FW, Towbin JA, Van Eyk J, Worrall BB; American Heart Association Advocacy Coordinating Committee.
Circulation 2012 Jul 3;126(1):142-57. Epub 2012 May 29 doi: 10.1161/CIR.0b013e31825b07f8. PMID: 22645291Free PMC Article

Recent clinical studies


Rai R, Sharma KL, Misra S, Kumar A, Mittal B
J Cancer Res Clin Oncol 2014 May;140(5):725-35. Epub 2014 Feb 21 doi: 10.1007/s00432-014-1621-7. PMID: 24556804

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