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Ovarian response to FSH stimulation

MedGen UID:
336404
•Concept ID:
C1848715
•
Finding
Synonym: OVARIAN RESPONSE TO FSH STIMULATION
 
OMIM®: 276400

Professional guidelines

PubMed

Preimplantation genetic testing for mitochondrial DNA mutation: ovarian response to stimulation, outcomes and follow-up.
Mayeur A, Benaloun E, Benguigui J, Duperier C, Hesters L, Chatzovoulou K, Monnot S, Grynberg M, Steffann J, Frydman N, Sonigo C
Reprod Biomed Online 2023 Jul;47(1):61-69. Epub 2023 Feb 28 doi: 10.1016/j.rbmo.2023.02.010. PMID: 37202317
History of cancer and fertility treatment outcomes: a registry linkage study in Massachusetts.
Farland LV, Stern JE, Hwang SS, Liu CL, Cabral H, Knowlton R, Gershman ST, Coddington CC 3rd, Missmer SA
J Assist Reprod Genet 2022 Feb;39(2):517-526. Epub 2022 Jan 17 doi: 10.1007/s10815-021-02376-x. PMID: 35037166Free PMC Article
Clinical management of low ovarian response to stimulation for IVF: a systematic review.
Tarlatzis BC, Zepiridis L, Grimbizis G, Bontis J
Hum Reprod Update 2003 Jan-Feb;9(1):61-76. doi: 10.1093/humupd/dmg007. PMID: 12638782

Recent clinical studies

Etiology

LH increases the response to FSH in granulosa-lutein cells from sub/poor-responder patients in vitro.
Sperduti S, Paradiso E, Anzivino C, Lazzaretti C, Limoncella S, D'Alessandro S, Roy N, Reggianini F, Ferrari T, Melli B, La Sala GB, Nicoli A, Daolio J, Villani MT, Tagliavini S, Trenti T, Potì F, Sandhowe R, Centonze C, Lispi M, Simoni M, Casarini L
Hum Reprod 2023 Jan 5;38(1):103-112. doi: 10.1093/humrep/deac246. PMID: 36367827
Reintroducing serum FSH measurement during ovarian stimulation for ART.
Lawrenz B, Melado L, Digma S, Sibal J, Coughlan C, Andersen CY, Fatemi HM
Reprod Biomed Online 2022 Mar;44(3):548-556. Epub 2021 Oct 31 doi: 10.1016/j.rbmo.2021.10.020. PMID: 34973935
Ovarian Stimulation Protocol in IVF: An Up-to-Date Review of the Literature.
Pacchiarotti A, Selman H, Valeri C, Napoletano S, Sbracia M, Antonini G, Biagiotti G, Pacchiarotti A
Curr Pharm Biotechnol 2016;17(4):303-15. doi: 10.2174/1389201017666160118103147. PMID: 26775651
Mild ovarian stimulation.
Check JH
J Assist Reprod Genet 2007 Dec;24(12):621-7. Epub 2007 Dec 4 doi: 10.1007/s10815-007-9179-9. PMID: 18058016Free PMC Article
FSH and folliculogenesis: from physiology to ovarian stimulation.
Vegetti W, Alagna F
Reprod Biomed Online 2006 Jun;12(6):684-94. doi: 10.1016/s1472-6483(10)61080-2. PMID: 16792843

Diagnosis

Factors Associated with Ovarian Hyperstimulation Syndrome (OHSS) Severity in Women With Polycystic Ovary Syndrome Undergoing IVF/ICSI.
Sun B, Ma Y, Li L, Hu L, Wang F, Zhang Y, Dai S, Sun Y
Front Endocrinol (Lausanne) 2020;11:615957. Epub 2021 Jan 19 doi: 10.3389/fendo.2020.615957. PMID: 33542709Free PMC Article
Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency.
Cakiroglu Y, Saltik A, Yuceturk A, Karaosmanoglu O, Kopuk SY, Scott RT, Tiras B, Seli E
Aging (Albany NY) 2020 Jun 5;12(11):10211-10222. doi: 10.18632/aging.103403. PMID: 32507764Free PMC Article
Individualized versus conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial.
Nyboe Andersen A, Nelson SM, Fauser BC, García-Velasco JA, Klein BM, Arce JC; ESTHER-1 study group
Fertil Steril 2017 Feb;107(2):387-396.e4. Epub 2016 Nov 29 doi: 10.1016/j.fertnstert.2016.10.033. PMID: 27912901
Intraovarian control of early folliculogenesis.
Hsueh AJ, Kawamura K, Cheng Y, Fauser BC
Endocr Rev 2015 Feb;36(1):1-24. Epub 2014 Sep 9 doi: 10.1210/er.2014-1020. PMID: 25202833Free PMC Article
Ovarian reserve.
Coccia ME, Rizzello F
Ann N Y Acad Sci 2008 Apr;1127:27-30. doi: 10.1196/annals.1434.011. PMID: 18443326

Therapy

The Role of Inositols in the Hyperandrogenic Phenotypes of PCOS: A Re-Reading of Larner's Results.
Fedeli V, Catizone A, Querqui A, Unfer V, Bizzarri M
Int J Mol Sci 2023 Mar 27;24(7) doi: 10.3390/ijms24076296. PMID: 37047265Free PMC Article
Randomized, assessor-blinded trial comparing highly purified human menotropin and recombinant follicle-stimulating hormone in high responders undergoing intracytoplasmic sperm injection.
Witz CA, Daftary GS, Doody KJ, Park JK, Seifu Y, Yankov VI, Heiser PW; Menopur in GnRH Antagonist Cycles with Single Embryo Transfer – High Responder (MEGASET-HR) Trial Group
Fertil Steril 2020 Aug;114(2):321-330. Epub 2020 May 13 doi: 10.1016/j.fertnstert.2020.03.029. PMID: 32416978
Individualized versus conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial.
Nyboe Andersen A, Nelson SM, Fauser BC, García-Velasco JA, Klein BM, Arce JC; ESTHER-1 study group
Fertil Steril 2017 Feb;107(2):387-396.e4. Epub 2016 Nov 29 doi: 10.1016/j.fertnstert.2016.10.033. PMID: 27912901
Ovarian Stimulation Protocol in IVF: An Up-to-Date Review of the Literature.
Pacchiarotti A, Selman H, Valeri C, Napoletano S, Sbracia M, Antonini G, Biagiotti G, Pacchiarotti A
Curr Pharm Biotechnol 2016;17(4):303-15. doi: 10.2174/1389201017666160118103147. PMID: 26775651
Mild ovarian stimulation.
Check JH
J Assist Reprod Genet 2007 Dec;24(12):621-7. Epub 2007 Dec 4 doi: 10.1007/s10815-007-9179-9. PMID: 18058016Free PMC Article

Prognosis

Factors Associated with Ovarian Hyperstimulation Syndrome (OHSS) Severity in Women With Polycystic Ovary Syndrome Undergoing IVF/ICSI.
Sun B, Ma Y, Li L, Hu L, Wang F, Zhang Y, Dai S, Sun Y
Front Endocrinol (Lausanne) 2020;11:615957. Epub 2021 Jan 19 doi: 10.3389/fendo.2020.615957. PMID: 33542709Free PMC Article
Randomized, assessor-blinded trial comparing highly purified human menotropin and recombinant follicle-stimulating hormone in high responders undergoing intracytoplasmic sperm injection.
Witz CA, Daftary GS, Doody KJ, Park JK, Seifu Y, Yankov VI, Heiser PW; Menopur in GnRH Antagonist Cycles with Single Embryo Transfer – High Responder (MEGASET-HR) Trial Group
Fertil Steril 2020 Aug;114(2):321-330. Epub 2020 May 13 doi: 10.1016/j.fertnstert.2020.03.029. PMID: 32416978
Individualization of controlled ovarian stimulation in vitro fertilization using ovarian reserve markers.
Grisendi V, La Marca A
Minerva Ginecol 2017 Jun;69(3):250-258. Epub 2017 Mar 7 doi: 10.23736/S0026-4784.17.04044-8. PMID: 28271699
Pharmacogenetics of ovarian response.
Lledo B, Ortiz JA, Llacer J, Bernabeu R
Pharmacogenomics 2014 Apr;15(6):885-93. doi: 10.2217/pgs.14.49. PMID: 24897293
Ovarian reserve.
Coccia ME, Rizzello F
Ann N Y Acad Sci 2008 Apr;1127:27-30. doi: 10.1196/annals.1434.011. PMID: 18443326

Clinical prediction guides

ERβ Regulation of Gonadotropin Responses during Folliculogenesis.
Lee EB, Chakravarthi VP, Wolfe MW, Rumi MAK
Int J Mol Sci 2021 Sep 26;22(19) doi: 10.3390/ijms221910348. PMID: 34638689Free PMC Article
Prediction of ovarian response in IVF/ICSI cycles.
Cortés-Vazquez A, Goitia-Landeros GA, Regalado MA, León-Hernández SR, Cortés-Algara AL, Bandala C, Moreno-García JD, Drakopoulos P
JBRA Assist Reprod 2021 Jul 21;25(3):422-427. doi: 10.5935/1518-0557.20210003. PMID: 34286939Free PMC Article
Individualization of controlled ovarian stimulation in vitro fertilization using ovarian reserve markers.
Grisendi V, La Marca A
Minerva Ginecol 2017 Jun;69(3):250-258. Epub 2017 Mar 7 doi: 10.23736/S0026-4784.17.04044-8. PMID: 28271699
Pharmacogenetics of ovarian response.
Lledo B, Ortiz JA, Llacer J, Bernabeu R
Pharmacogenomics 2014 Apr;15(6):885-93. doi: 10.2217/pgs.14.49. PMID: 24897293
Ovarian reserve.
Coccia ME, Rizzello F
Ann N Y Acad Sci 2008 Apr;1127:27-30. doi: 10.1196/annals.1434.011. PMID: 18443326

Recent systematic reviews

Systematic review of acupuncture to improve ovarian function in women with poor ovarian response.
Wang RR, Su MH, Liu LY, Lai YY, Guo XL, Gan D, Zheng XY, Yang H, Yu SY, Liang FR, Wei W, Zhong Y, Yang J
Front Endocrinol (Lausanne) 2023;14:1028853. Epub 2023 Mar 13 doi: 10.3389/fendo.2023.1028853. PMID: 36992800Free PMC Article
Use of gonadotropins in ovarian stimulation in Spain: Delphi consensus.
Barrenetxea G, Hernández C, Herrero J, Martínez Navarro L, Muñoz M, Rubio JM, Sánchez F, Zabaleta J
J Obstet Gynaecol 2023 Dec;43(1):2174692. doi: 10.1080/01443615.2023.2174692. PMID: 36772946
Prediction, assessment, and management of suboptimal GnRH agonist trigger: a systematic review.
Ganer Herman H, Horowitz E, Mizrachi Y, Farhi J, Raziel A, Weissman A
J Assist Reprod Genet 2022 Feb;39(2):291-303. Epub 2022 Mar 19 doi: 10.1007/s10815-021-02359-y. PMID: 35306603Free PMC Article
Clomiphene citrate and letrozole to reduce follicle-stimulating hormone consumption during ovarian stimulation: systematic review and meta-analysis.
Bechtejew TN, Nadai MN, Nastri CO, Martins WP
Ultrasound Obstet Gynecol 2017 Sep;50(3):315-323. Epub 2017 Aug 10 doi: 10.1002/uog.17442. PMID: 28236310
Clinical management of low ovarian response to stimulation for IVF: a systematic review.
Tarlatzis BC, Zepiridis L, Grimbizis G, Bontis J
Hum Reprod Update 2003 Jan-Feb;9(1):61-76. doi: 10.1093/humupd/dmg007. PMID: 12638782

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