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Items: 5

1.

Hairy cell leukemia

A neoplasm of small B-lymphocytes with "hairy" projections in bone marrow, spleen, and peripheral blood. Most patients present with splenomegaly and pancytopenia. (WHO, 2001) [from NCI]

MedGen UID:
9727
Concept ID:
C0023443
Neoplastic Process
2.

Adhesion

A fibrous band of tissue that connects normally separate body regions.(NICHD) [from NCI]

MedGen UID:
7891
Concept ID:
C0001511
Pathologic Function
3.

Diphenhydramine

A first generation antihistamine and ethanolamine with sedative and anti-allergic properties. Diphenhydramine competitively inhibits the histamine-1 (H1) receptor, thereby alleviating the symptoms caused by endogenous histamine on bronchial, capillary and gastrointestinal smooth muscles. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. [from NCI]

MedGen UID:
4330
Concept ID:
C0012522
Organic Chemical; Pharmacologic Substance
4.

Nedocromil sodium

The sodium salt form of nedocromil, a pyranoquinolone derivative with anti-inflammatory properties. Nedocromil sodium inhibits the activation and release of inflammatory mediators (leukotrienes, histamine and prostaglandins) from a variety of cells involved in hypersensitivity reactions, including mast cells, eosinophils, neutrophils, macrophages, monocytes and platelets. As a result, nedocromil sodium inhibits both immediate and late bronchoconstriction, decreases bronchial hyperresponsiveness and inhibits recruitment of other inflammatory cells into the airway epithelium. [from NCI]

MedGen UID:
168173
Concept ID:
C0886658
Organic Chemical; Pharmacologic Substance
5.

Nedocromil

A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets. [from MeSH]

MedGen UID:
32213
Concept ID:
C0068483
Organic Chemical; Pharmacologic Substance
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