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Items: 1 to 20 of 41

1.

brain-derived neurotrophic factor, human

Brain-derived neurotrophic factor (247 aa, ~28 kDa) is encoded by the human BDNF gene. This protein plays a role in both the development of the nervous system and neuronal survival. [from NCI]

MedGen UID:
760637
Concept ID:
C3486709
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
2.

Mood disorder

Most people feel sad or irritable from time to time. They may say they're in a bad mood. A mood disorder is different. It affects a person's everyday emotional state. Nearly one in ten people aged 18 and older have mood disorders. These include depression and bipolar disorder (also called manic depression). Mood disorders can increase a person's risk for heart disease, diabetes, and other diseases. Treatments include medication, psychotherapy, or a combination of both. With treatment, most people with mood disorders can lead productive lives.  [from MedlinePlus]

MedGen UID:
99866
Concept ID:
C0525045
Mental or Behavioral Dysfunction
3.

paroxetine

A serotonin uptake inhibitor that is effective in the treatment of depression. [from MeSH]

MedGen UID:
74439
Concept ID:
C0070122
Organic Chemical; Pharmacologic Substance
4.

Citalopram

A furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition. [from MeSH]

MedGen UID:
979
Concept ID:
C0008845
Organic Chemical; Pharmacologic Substance
5.

Mood Disorders

MedGen UID:
881097
Concept ID:
CN236678
Disease or Syndrome
6.

Selective Serotonin Reuptake Inhibitors

Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia. [from NCI]

MedGen UID:
452467
Concept ID:
C0360105
Pharmacologic Substance
7.

Ameliorated by

Weakened or thinned. Attenuated strains of disease-causing bacteria and viruses are often used as vaccines. The weakened strains are used as vaccines because they stimulate a protective immune response while causing no disease or only mild disease in the person receiving the vaccine. [from NCI_NCI-GLOSS]

MedGen UID:
83049
Concept ID:
C0332161
Qualitative Concept
8.

Antidepressive Agents

Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They work to balance some of the natural chemicals in our brains. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try a few before finding what works best for you. Antidepressants may cause mild side effects that usually do not last long. These may include headache, nausea, sleep problems, restlessness, and sexual problems. Tell your doctor if you have any side effects. You should also let your doctor know if you take any other medicines, vitamins, or herbal supplements. It is important to keep taking your medicines, even if you feel better. Do not stop taking your medicines without talking to your doctor. You often need to stop antidepressants gradually. NIH: National Institute of Mental Health.  [from MedlinePlus]

MedGen UID:
1588
Concept ID:
C0003289
Pharmacologic Substance
9.

Triptans

Derivatives of TRYPTAMINES that are SEROTONIN RECEPTOR AGONISTS acting at 5-HT1 RECEPTORS. Some are used to treat MIGRAINE DISORDERS. [from MeSH]

MedGen UID:
298143
Concept ID:
C1567966
Organic Chemical; Pharmacologic Substance
10.

Membrane Transport Modulators

Agents that affect ION PUMPS; ION CHANNELS; ABC TRANSPORTERS; and other MEMBRANE TRANSPORT PROTEINS. [from MeSH]

MedGen UID:
288786
Concept ID:
C1563710
Pharmacologic Substance
11.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
12.

Lexapro

Trade name of escitalopram, the active S-enantiomer of the racemic citalopram. [from MeSH]

MedGen UID:
223938
Concept ID:
C1170371
Organic Chemical; Pharmacologic Substance
13.

Escitalopram

S-enantiomer of citalopram. [from MeSH]

MedGen UID:
203862
Concept ID:
C1099456
Organic Chemical; Pharmacologic Substance
14.

FG-7051

MedGen UID:
149120
Concept ID:
C0733372
Organic Chemical; Pharmacologic Substance
15.

Aropax

MedGen UID:
149119
Concept ID:
C0733370
Organic Chemical; Pharmacologic Substance
16.

Lu-10-171

MedGen UID:
148705
Concept ID:
C0701047
Organic Chemical; Pharmacologic Substance
17.

BRL-29060

MedGen UID:
147610
Concept ID:
C0733371
Organic Chemical; Pharmacologic Substance
18.

Seroxat

MedGen UID:
146814
Concept ID:
C0678139
Organic Chemical; Pharmacologic Substance
19.

Serotonin Uptake Inhibitors

any agent or substance which suppresses, prevents or opposes the actions of serotonin. [from CRISP]

MedGen UID:
102458
Concept ID:
C0162758
Pharmacologic Substance
20.

Serotonin Agonists

Any agent that binds to and activates serotonin receptors. [from NCI]

MedGen UID:
102457
Concept ID:
C0162757
Pharmacologic Substance
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