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Items: 1 to 20 of 46

1.

Malignant tumor of prostate

A cancer of the prostate. [from HPO]

MedGen UID:
138169
Concept ID:
C0376358
Neoplastic Process
2.

Prostate cancer

A cancer of the prostate. [from HPO]

MedGen UID:
506673
Concept ID:
CN167851
Finding
3.

Invasion

The movement of one cell type into an area normally occupied by a different cell type. [from NCI]

MedGen UID:
397081
Concept ID:
C2699153
Pathologic Function
4.

Malignancies

MedGen UID:
924235
Concept ID:
C4282132
Neoplastic Process
5.

Hyperplasia of prostate

Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both. [from MeSH]

MedGen UID:
422472
Concept ID:
C2937421
Disease or Syndrome
6.

Benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH) refers to the nonmalignant growth of the prostate gland, and is histologically defined as hyperplasia of the prostate gland. BPH is an age-related phenomenon in men beginning at about age 40 years. BPH may result in prostatic enlargement and clinical symptoms most commonly affecting the lower urinary tract. These symptoms may be obstructive, including hesitancy, weak flow, and urinary retention, or irritative, including increased frequency and urgency. However, not all men with histologic BPH will develop prostatic enlargement or urinary symptoms (review by Roehrborn, 2005). [from GTR]

MedGen UID:
312369
Concept ID:
C1704272
Neoplastic Process
7.

Intraepithelial Neoplasia

A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. According to the degree of nuclear atypia, number of mitotic figures, and presence of architectural distortion, it is classified as low grade (mild dysplasia) or high grade (moderate or severe dysplasia). [from NCI]

MedGen UID:
164203
Concept ID:
C0878500
Neoplastic Process
8.

Frequency

MedGen UID:
91210
Concept ID:
C0376249
Temporal Concept
9.

Atrophy

Any weakening or degeneration, especially through lack of use. [from NCI]

MedGen UID:
83084
Concept ID:
C0333641
Pathologic Function
10.

Prostatic Intraepithelial Neoplasia

A neoplastic proliferation of the epithelial cells that line the acini and the ducts of the prostate gland. The neoplastic epithelial cells are confined within the acini and the ducts and they do not invade the surrounding prostatic stroma. Morphologically, it is classified as low or high grade. [from NCI]

MedGen UID:
76480
Concept ID:
C0282612
Neoplastic Process
11.

Hyperplasia

An abnormal increase in the number of cells in an organ or a tissue with consequent enlargement. [from NCI]

MedGen UID:
43784
Concept ID:
C0020507
Pathologic Function
12.

Episodic

Applied to a sign, symptom, or other manifestation that occurs at least twice and potentially multiple times but separated by an interval in whichthe sign, symptom, or manifestation is not present. [from HPO]

MedGen UID:
910017
Concept ID:
CN240220
Organism Attribute
13.

Posterior cortical atrophy

Posterior Cortical Atrophy (PCA) is a rare progressive neurodegenerative disorder with a typical onset between 50-65 years of age characterized by progressive impairment of higher visual processing skills and other posterior cortical functions without any evidence of ocular abnormalities. [from ORDO]

MedGen UID:
799015
Concept ID:
CN205270
Disease or Syndrome
14.

Epithelioma, malignant

MedGen UID:
639977
Concept ID:
C0553707
Neoplastic Process
15.

Benign prostatic hyperplasia

The presence of non-malignant hyperplasia of the prostate. [from HPO]

MedGen UID:
506248
Concept ID:
CN007662
Finding
16.

Proliferative Inflammatory Atrophy

A lesion in the prostate gland characterized by glandular atrophy, chronic inflammation, and epithelial hyperplasia. It has been suggested that it is a precancerous lesion and it may lead to the development of prostatic intraepithelial neoplasia and prostatic carcinoma. [from NCI]

MedGen UID:
474872
Concept ID:
C3273239
Disease or Syndrome
17.

High Grade Prostatic Intraepithelial Neoplasia

Prostatic intraepithelial neoplasia characterized by the presence of morphologically malignant cells lining the acini and ducts. The malignant cells are enlarged, contain prominent nucleoli, and have increased nuclear/cytoloplasmic ratio. The malignant cells may grow within the ducts and acini in four architectural patterns: flat, tufting, micropapillary, and cribriform. The presence of high grade prostatic intraepithelial neoplasia in needle biopsy is a risk factor for the subsequent detection of carcinoma on repeat biopsy. [from NCI]

MedGen UID:
217002
Concept ID:
C1168327
Neoplastic Process
18.

Severe

Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
104640
Concept ID:
C0205082
Qualitative Concept
19.

Localized

Being confined or restricted to a particular location. [from HPO]

MedGen UID:
98236
Concept ID:
C0392752
Spatial Concept
20.

Benign Epithelial Neoplasm

A neoplasm arising from the epithelial cells. It is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign epithelial neoplasms remain confined to the original site of growth and only rarely metastasize to other anatomic sites. [from NCI]

MedGen UID:
90747
Concept ID:
C0334232
Neoplastic Process
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