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Items: 14

1.

Leukemia

A cancer of the blood and bone marrow characterized by an abnormal proliferation of leukocytes. [from HPO]

MedGen UID:
505002
Concept ID:
CN001727
Finding
2.

T-cell prolymphocytic leukemia

A lymphoid leukemia characterized by a profound LYMPHOCYTOSIS with or without LYMPHADENOPATHY, hepatosplenomegaly, frequently rapid progression, and short survival. It was formerly called T-cell chronic lymphocytic leukemia. [from MeSH]

MedGen UID:
391707
Concept ID:
C2363142
Neoplastic Process
3.

Lymphadenopathy

Enlargment (swelling) of a lymph node. [from HPO]

MedGen UID:
96929
Concept ID:
C0497156
Finding
4.

Splenomegaly

Enlargement of the spleen. [from MeSH]

MedGen UID:
52469
Concept ID:
C0038002
Finding
5.

Chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a common neoplasia of B lymphocytes in which these cells progressively accumulate in the bone marrow, blood, and lymphoid tissues. The clinical evolution of the disorder is heterogeneous, with some patients having indolent disease and others having aggressive disease and short survival (summary by Quesada et al., 2012). Genetic Heterogeneity of Susceptibility to Chronic Lymphocytic Leukemia Susceptibility loci have been mapped to chromosomes 11p11 (CLLS1; 609630) and 13q14 (CLLS2; 109543) by genomewide linkage analysis and translocation studies, respectively. Susceptibility mapping to chromosome 9q34 (CLLS3; 612557) is associated with downregulation of the DAPK1 gene (600831). Genomewide association studies have identified susceptibility loci on chromosomes 6p25.3 (CLLS4; 612558) and 11q24.1 (CLLS5; 612559). [from OMIM]

MedGen UID:
44120
Concept ID:
C0023434
Neoplastic Process
6.

Lymphoid leukemia

Leukemia associated with hyperplasia of the lymphoid tissues and increased numbers of circulating malignant lymphocytes and lymphoblasts. [from HPO]

MedGen UID:
9728
Concept ID:
C0023448
Neoplastic Process
7.

Transplantation

MedGen UID:
881115
Concept ID:
CN236682
Disease or Syndrome
8.

progressive

MedGen UID:
851455
Concept ID:
CN232553
Finding
9.

Chronic lymphatic leukemia

A chronic lymphocytic/lymphatic/lymphoblastic leukemia (CLL) is a neoplastic disease characterized by proliferation and accumulation (blood, marrow and lymphoid organs) of morphologically mature but immunologically dysfunctional lymphocytes. A CLL is always a B-cell lymphocytic leukemia as there are no reports of cases of T-cell lymphocytic leukemias. [from HPO]

MedGen UID:
505830
Concept ID:
CN004916
Finding
10.

Lymphoproliferative disorder

MedGen UID:
505822
Concept ID:
CN004892
Finding
11.

Leukocytosis

A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood. [from NCI]

MedGen UID:
155453
Concept ID:
C0750426
Finding
12.

Asymptomatic

The finding of no indications of a particular disease or injury. [from NCI]

MedGen UID:
65413
Concept ID:
C0231221
Finding
13.

Lymphatic Diseases

The lymphatic system is a network of tissues and organs. It is made up of. -Lymph - a fluid that contains white blood cells that defend against germs. -Lymph vessels - vessels that carry lymph throughout your body. They are different from blood vessels. -Lymph nodes - glands found throughout the lymph vessels. Along with your spleen, these nodes are where white blood cells fight infection. Your bone marrow and thymus produce the cells in lymph. They are part of the system, too. The lymphatic system clears away infection and keeps your body fluids in balance. If it's not working properly, fluid builds in your tissues and causes swelling, called lymphedema. Other lymphatic system problems can include infections, blockage, and cancer.  [from MedlinePlus]

MedGen UID:
9829
Concept ID:
C0024228
Disease or Syndrome
14.

T-cell chronic lymphocytic lymphoma/leukemia

MedGen UID:
428537
Concept ID:
CN004905
Neoplastic Process
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