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Malaria

MedGen UID:
7443
Concept ID:
C0024530
Disease or Syndrome
Synonyms: Fever, Marsh; Fever, Remittent; Infection, Plasmodium; Infections, Plasmodium; Marsh Fever; Paludism; Plasmodium Infection; Plasmodium Infections; Remittent Fever
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
SNOMED CT: Malaria (61462000); Paludism (61462000); Plasmodiosis (61462000); Disease due to Plasmodiidae (105649009); Disease caused by Plasmodiidae (105649009); Malarial fever (248437004)
 
Orphanet: ORPHA673

Definition

Malaria is a serious disease caused by a parasite. You get it when an infected mosquito bites you. Malaria is a major cause of death worldwide, but it is almost wiped out in the United States. The disease is mostly a problem in developing countries with warm climates. If you travel to these countries, you are at risk. There are four different types of malaria caused by four related parasites. The most deadly type occurs in Africa south of the Sahara Desert. Malaria symptoms include chills, flu-like symptoms, fever, vomiting, diarrhea, and jaundice. A blood test can diagnose it. It can be life-threatening. However, you can treat malaria with drugs. The type of drug depends on which kind of malaria you have and where you were infected. Malaria can be prevented. When traveling to malaria-prone regions. - See your doctor for medicines that protect you . - Wear insect repellent with DEET . - Cover up. - Sleep under mosquito netting . Centers for Disease Control and Prevention.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalaria
Follow this link to review classifications for Malaria in Orphanet.

Recent clinical studies

Etiology

Zheng X, Lin M, Xie DD, Li J, Chen JT, Eyi UM, Monte-Nguba SM, Ehapo JC, Yang H, Yang HT, Yang LY
Afr J AIDS Res 2017 Mar;16(1):65-70. doi: 10.2989/16085906.2016.1257495. PMID: 28367743
Hopkins H, Bruxvoort KJ, Cairns ME, Chandler CI, Leurent B, Ansah EK, Baiden F, Baltzell KA, Björkman A, Burchett HE, Clarke SE, DiLiberto DD, Elfving K, Goodman C, Hansen KS, Kachur SP, Lal S, Lalloo DG, Leslie T, Magnussen P, Jefferies LM, Mårtensson A, Mayan I, Mbonye AK, Msellem MI, Onwujekwe OE, Owusu-Agyei S, Reyburn H, Rowland MW, Shakely D, Vestergaard LS, Webster J, Wiseman VL, Yeung S, Schellenberg D, Staedke SG, Whitty CJ
BMJ 2017 Mar 29;356:j1054. PMID: 28356302Free PMC Article
Kotepui M, PhunPhuech B, Phiwklam N, Uthaisar K
Infect Dis Poverty 2017 Mar 2;6(1):27. doi: 10.1186/s40249-017-0238-x. PMID: 28249623Free PMC Article
Ma C, Claude KM, Kibendelwa ZT, Brooks H, Zheng X, Hawkes M
Pathog Glob Health 2017 Mar;111(2):98-106. Epub 2017 Feb 21 doi: 10.1080/20477724.2017.1288971. PMID: 28220714Free PMC Article
Gupta P, Narang M, Gomber S, Saha R
Paediatr Int Child Health 2017 May;37(2):139-143. Epub 2016 Jul 26 doi: 10.1080/20469047.2016.1209883. PMID: 27458993

Diagnosis

Hopkins H, Bruxvoort KJ, Cairns ME, Chandler CI, Leurent B, Ansah EK, Baiden F, Baltzell KA, Björkman A, Burchett HE, Clarke SE, DiLiberto DD, Elfving K, Goodman C, Hansen KS, Kachur SP, Lal S, Lalloo DG, Leslie T, Magnussen P, Jefferies LM, Mårtensson A, Mayan I, Mbonye AK, Msellem MI, Onwujekwe OE, Owusu-Agyei S, Reyburn H, Rowland MW, Shakely D, Vestergaard LS, Webster J, Wiseman VL, Yeung S, Schellenberg D, Staedke SG, Whitty CJ
BMJ 2017 Mar 29;356:j1054. PMID: 28356302Free PMC Article
Kotepui M, PhunPhuech B, Phiwklam N, Uthaisar K
Infect Dis Poverty 2017 Mar 2;6(1):27. doi: 10.1186/s40249-017-0238-x. PMID: 28249623Free PMC Article
Ma C, Claude KM, Kibendelwa ZT, Brooks H, Zheng X, Hawkes M
Pathog Glob Health 2017 Mar;111(2):98-106. Epub 2017 Feb 21 doi: 10.1080/20477724.2017.1288971. PMID: 28220714Free PMC Article
Gupta P, Narang M, Gomber S, Saha R
Paediatr Int Child Health 2017 May;37(2):139-143. Epub 2016 Jul 26 doi: 10.1080/20469047.2016.1209883. PMID: 27458993
Cibulskis RE, Alonso P, Aponte J, Aregawi M, Barrette A, Bergeron L, Fergus CA, Knox T, Lynch M, Patouillard E, Schwarte S, Stewart S, Williams R
Infect Dis Poverty 2016 Jun 9;5(1):61. doi: 10.1186/s40249-016-0151-8. PMID: 27282148Free PMC Article

Therapy

Hopkins H, Bruxvoort KJ, Cairns ME, Chandler CI, Leurent B, Ansah EK, Baiden F, Baltzell KA, Björkman A, Burchett HE, Clarke SE, DiLiberto DD, Elfving K, Goodman C, Hansen KS, Kachur SP, Lal S, Lalloo DG, Leslie T, Magnussen P, Jefferies LM, Mårtensson A, Mayan I, Mbonye AK, Msellem MI, Onwujekwe OE, Owusu-Agyei S, Reyburn H, Rowland MW, Shakely D, Vestergaard LS, Webster J, Wiseman VL, Yeung S, Schellenberg D, Staedke SG, Whitty CJ
BMJ 2017 Mar 29;356:j1054. PMID: 28356302Free PMC Article
Gupta P, Narang M, Gomber S, Saha R
Paediatr Int Child Health 2017 May;37(2):139-143. Epub 2016 Jul 26 doi: 10.1080/20469047.2016.1209883. PMID: 27458993
Cibulskis RE, Alonso P, Aponte J, Aregawi M, Barrette A, Bergeron L, Fergus CA, Knox T, Lynch M, Patouillard E, Schwarte S, Stewart S, Williams R
Infect Dis Poverty 2016 Jun 9;5(1):61. doi: 10.1186/s40249-016-0151-8. PMID: 27282148Free PMC Article
Braack L
Malar J 2016 Apr 12;15:207. doi: 10.1186/s12936-016-1265-y. PMID: 27071552Free PMC Article
Barger-Kamate B, Forman M, Sangare CO, Haidara AS, Maiga H, Vaidya D, Djimde A, Arav-Boger R
J Clin Virol 2016 Apr;77:40-5. Epub 2016 Feb 11 doi: 10.1016/j.jcv.2016.02.006. PMID: 26895228Free PMC Article

Prognosis

Ma C, Claude KM, Kibendelwa ZT, Brooks H, Zheng X, Hawkes M
Pathog Glob Health 2017 Mar;111(2):98-106. Epub 2017 Feb 21 doi: 10.1080/20477724.2017.1288971. PMID: 28220714Free PMC Article
Shimaponda-Mataa NM, Tembo-Mwase E, Gebreslasie M, Achia TN, Mukaratirwa S
Acta Trop 2017 Feb;166:81-91. Epub 2016 Nov 6 doi: 10.1016/j.actatropica.2016.11.007. PMID: 27829141
Gupta P, Narang M, Gomber S, Saha R
Paediatr Int Child Health 2017 May;37(2):139-143. Epub 2016 Jul 26 doi: 10.1080/20469047.2016.1209883. PMID: 27458993
Cibulskis RE, Alonso P, Aponte J, Aregawi M, Barrette A, Bergeron L, Fergus CA, Knox T, Lynch M, Patouillard E, Schwarte S, Stewart S, Williams R
Infect Dis Poverty 2016 Jun 9;5(1):61. doi: 10.1186/s40249-016-0151-8. PMID: 27282148Free PMC Article
Touré M, Sanogo D, Dembele S, Diawara SI, Oppfeldt K, Schiøler KL, Haidara DB, Traoré SF, Alifrangis M, Konradsen F, Doumbia S
Malar J 2016 Apr 18;15:219. doi: 10.1186/s12936-016-1251-4. PMID: 27091046Free PMC Article

Clinical prediction guides

Hopkins H, Bruxvoort KJ, Cairns ME, Chandler CI, Leurent B, Ansah EK, Baiden F, Baltzell KA, Björkman A, Burchett HE, Clarke SE, DiLiberto DD, Elfving K, Goodman C, Hansen KS, Kachur SP, Lal S, Lalloo DG, Leslie T, Magnussen P, Jefferies LM, Mårtensson A, Mayan I, Mbonye AK, Msellem MI, Onwujekwe OE, Owusu-Agyei S, Reyburn H, Rowland MW, Shakely D, Vestergaard LS, Webster J, Wiseman VL, Yeung S, Schellenberg D, Staedke SG, Whitty CJ
BMJ 2017 Mar 29;356:j1054. PMID: 28356302Free PMC Article
Ma C, Claude KM, Kibendelwa ZT, Brooks H, Zheng X, Hawkes M
Pathog Glob Health 2017 Mar;111(2):98-106. Epub 2017 Feb 21 doi: 10.1080/20477724.2017.1288971. PMID: 28220714Free PMC Article
Kalantari M, Soltani Z, Ebrahimi M, Yousefi M, Amin M, Shafiei A, Azizi K
Pathog Glob Health 2017 Feb;111(1):49-55. Epub 2017 Jan 12 doi: 10.1080/20477724.2016.1271094. PMID: 28078947Free PMC Article
Gupta P, Narang M, Gomber S, Saha R
Paediatr Int Child Health 2017 May;37(2):139-143. Epub 2016 Jul 26 doi: 10.1080/20469047.2016.1209883. PMID: 27458993
Touré M, Sanogo D, Dembele S, Diawara SI, Oppfeldt K, Schiøler KL, Haidara DB, Traoré SF, Alifrangis M, Konradsen F, Doumbia S
Malar J 2016 Apr 18;15:219. doi: 10.1186/s12936-016-1251-4. PMID: 27091046Free PMC Article

Recent systematic reviews

Hopkins H, Bruxvoort KJ, Cairns ME, Chandler CI, Leurent B, Ansah EK, Baiden F, Baltzell KA, Björkman A, Burchett HE, Clarke SE, DiLiberto DD, Elfving K, Goodman C, Hansen KS, Kachur SP, Lal S, Lalloo DG, Leslie T, Magnussen P, Jefferies LM, Mårtensson A, Mayan I, Mbonye AK, Msellem MI, Onwujekwe OE, Owusu-Agyei S, Reyburn H, Rowland MW, Shakely D, Vestergaard LS, Webster J, Wiseman VL, Yeung S, Schellenberg D, Staedke SG, Whitty CJ
BMJ 2017 Mar 29;356:j1054. PMID: 28356302Free PMC Article
Homan T, Hiscox A, Mweresa CK, Masiga D, Mukabana WR, Oria P, Maire N, Pasquale AD, Silkey M, Alaii J, Bousema T, Leeuwis C, Smith TA, Takken W
Lancet 2016 Sep 17;388(10050):1193-201. Epub 2016 Aug 9 doi: 10.1016/S0140-6736(16)30445-7. PMID: 27520594
van Eijk AM, Ramanathapuram L, Sutton PL, Kanagaraj D, Sri Lakshmi Priya G, Ravishankaran S, Asokan A, Tandel N, Patel A, Desai N, Singh R, Sullivan SA, Carlton JM, Srivastava HC, Eapen A
Malar J 2016 Feb 6;15:67. doi: 10.1186/s12936-016-1120-1. PMID: 26852118Free PMC Article
Kassam R, Collins JB, Liow E, Rasool N
Acta Trop 2015 Dec;152:252-68. Epub 2015 Aug 7 doi: 10.1016/j.actatropica.2015.07.028. PMID: 26257070
Das DK, Mukherjee R, Chakraborty C
J Microsc 2015 Oct;260(1):1-19. Epub 2015 Jun 5 doi: 10.1111/jmi.12270. PMID: 26047029

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