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Items: 1 to 20 of 25

1.

Human insulin product

Regular insulin preparations that contain the HUMAN insulin peptide sequence. [from MeSH]

MedGen UID:
162753
Concept ID:
C0795635
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
2.

Hyperplasia

An abnormal increase in the number of cells in an organ or a tissue with consequent enlargement. [from NCI]

MedGen UID:
43784
Concept ID:
C0020507
Pathologic Function
3.

Obesity

A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). [from MeSH]

MedGen UID:
18127
Concept ID:
C0028754
Disease or Syndrome
4.

Glucagon

A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511) [from MeSH]

MedGen UID:
6620
Concept ID:
C0017687
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
5.

Regular insulin

A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). [from MeSH]

MedGen UID:
5827
Concept ID:
C0021641
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
6.

Increased insulin level

Abnormally high levels of insulin in the blood. [from NCI]

MedGen UID:
894826
Concept ID:
C0852795
Finding
7.

Mild obesity

MedGen UID:
832924
Concept ID:
CN228310
Finding
8.

Obesity

MedGen UID:
368429
Concept ID:
C1963185
Finding
9.

Mild

Having a relatively minor degree of severity. For quantitative traits, a deviation of between two and three standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
268697
Concept ID:
C1513302
Finding
10.

Ability to balance

The maintenance of a stable, upright body position. [from NCI]

MedGen UID:
154340
Concept ID:
C0560184
Finding
11.

Mass of body structure

A benign or malignant pathologic structure in any part of the body, resulting from a neoplastic accumulation of cells, inflammatory cells, or cystic changes. [from NCI]

MedGen UID:
108287
Concept ID:
C0577559
Finding
12.

Ameliorated by

An ameliorating factor is defined as an external factor that leads to the manifestation of a sign or symptom in a person improving or becoming more bearable. [from HPO]

MedGen UID:
83049
Concept ID:
C0332161
Qualitative Concept
13.

Hyperinsulinemia

A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS. [from MeSH]

MedGen UID:
43779
Concept ID:
C0020459
Disease or Syndrome; Finding
14.

Fat

The glyceryl esters of a fatty acid, or of a mixture of fatty acids. They are generally odorless, colorless, and tasteless if pure, but they may be flavored according to origin. Fats are insoluble in water, soluble in most organic solvents. They occur in animal and vegetable tissue and are generally obtained by boiling or by extraction under pressure. They are important in the diet (DIETARY FATS) as a source of energy. (Grant & Hackh's Chemical Dictionary, 5th ed) [from MeSH]

MedGen UID:
5132
Concept ID:
C0015677
Organic Chemical; Pharmacologic Substance
15.

Insulins

Peptide hormones that cause an increase in the absorption of GLUCOSE by cells within organs such as LIVER, MUSCLE and ADIPOSE TISSUE. During normal metabolism insulins are produced by the PANCREATIC BETA CELLS in response to increased GLUCOSE. Natural and chemically-modified forms of insulin are also used in the treatment of GLUCOSE METABOLISM DISORDERS such as DIABETES MELLITUS. [from MeSH]

MedGen UID:
760846
Concept ID:
C3537244
Pharmacologic Substance
16.

Tyrosine

A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. [from MeSH]

MedGen UID:
21746
Concept ID:
C0041485
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
17.

Pancreatic hormone product

Peptide hormones secreted into the blood by cells in the ISLETS OF LANGERHANS of the pancreas. The alpha cells secrete glucagon; the beta cells secrete insulin; the delta cells secrete somatostatin; and the PP cells secrete pancreatic polypeptide. [from MeSH]

MedGen UID:
14585
Concept ID:
C0030292
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
18.

Novolin

MedGen UID:
10388
Concept ID:
C0028467
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
19.

Iletin

MedGen UID:
7012
Concept ID:
C0020884
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
20.

Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. [from MeSH]

MedGen UID:
6887
Concept ID:
C0019934
Pharmacologic Substance
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