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Items: 1 to 20 of 38

1.

Cisplatin

An alkylating-like inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. [from NCI]

MedGen UID:
40318
Concept ID:
C0008838
Inorganic Chemical; Pharmacologic Substance
2.

Hearing impairment

A general term for the complete or partial loss of the ability to hear from one or both ears. [from MeSH]

MedGen UID:
235586
Concept ID:
C1384666
Disease or Syndrome
3.

Impairment

MedGen UID:
151925
Concept ID:
C0684336
Pathologic Function
4.

Malignant tumor of testis

Testicular germ cell tumors (TGCTs) affect 1 in 500 men and are the most common cancer in males aged 15 to 40 in western European populations. The incidence of TGCT rose dramatically during the 20th century. Known risk factors for TGCT include a history of undescended testis (UDT), testicular dysgenesis, infertility, previously diagnosed TGCT, and a family history of the disease. Brothers of men with TGCT have an 8- to 10-fold risk of developing TGCT, whereas the relative risk to fathers and sons is 4-fold. This familial relative risk is much higher than that for most other types of cancer (summary by Rapley et al., 2000). Genetic Heterogeneity of Testicular Germ Cell Tumors A locus for testicular germ cell tumors (TGCT1; 300228) has been identified on chromosome Xq27. [from GTR]

MedGen UID:
56313
Concept ID:
C0153594
Neoplastic Process
5.

Hearing impairment

A condition in which a person partially loses the ability to hear sounds in one or both ears. [from NCI]

MedGen UID:
5453
Concept ID:
C0018772
Finding
6.

Separated from cohabitee

Indicates a person living apart from his/her spouse by legal arrangement. [from NCI]

MedGen UID:
88651
Concept ID:
C0086972
Finding
7.

Ototoxicity

MedGen UID:
880947
Concept ID:
CN236668
Disease or Syndrome
8.

Offered

MedGen UID:
731829
Concept ID:
C1444648
Finding
9.

Regression

Return to a former state; a subsidence of the symptoms of a disease process; in cancer, a decrease in the size of a tumor or in the extent of cancer in the body. [from NCI]

MedGen UID:
195771
Concept ID:
C0684320
Pathologic Function
10.

Negative

An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure. [Note: Negative does not necessarily imply the complete absence of the specified item.].  [from HL7]

MedGen UID:
61377
Concept ID:
C0205160
Finding
11.

Male Urogenital Diseases

Pathological processes of the male URINARY TRACT and the reproductive system (GENITALIA, MALE). [from MeSH]

MedGen UID:
318601
Concept ID:
C1720894
Disease or Syndrome
12.

Dysacousia

MedGen UID:
267601
Concept ID:
C1510450
Sign or Symptom
13.

Platinol

MedGen UID:
195927
Concept ID:
C0699666
Inorganic Chemical; Pharmacologic Substance
14.

NSC-119875

MedGen UID:
181696
Concept ID:
C0936226
Inorganic Chemical; Pharmacologic Substance
15.

Platino

MedGen UID:
152100
Concept ID:
C0699665
Inorganic Chemical; Pharmacologic Substance
16.

Platidiam

MedGen UID:
152099
Concept ID:
C0699664
Inorganic Chemical; Pharmacologic Substance
17.

Biocisplatinum

MedGen UID:
152098
Concept ID:
C0699663
Inorganic Chemical; Pharmacologic Substance
18.

Genetic predisposition

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions. [from MeSH]

MedGen UID:
137259
Concept ID:
C0314657
Organism Attribute
19.

Hearing problem

A disorder characterized by the partial or complete loss of the ability to detect sounds due to damage to the ear structures or inability of the brain to properly interpret or process the auditory signals it receives from the anatomic structures of the ear. [from NCI]

MedGen UID:
82636
Concept ID:
C0260662
Disease or Syndrome
20.

Paracusis

Altered sense of hearing, other than simple decreased hearing or deafness [from SNOMEDCT_US]

MedGen UID:
57838
Concept ID:
C0155536
Sign or Symptom
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