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Items: 1 to 20 of 61

1.

Oligodendroglioma

A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655) [from MeSH]

MedGen UID:
45190
Concept ID:
C0028945
Neoplastic Process
2.

Oligodendroglioma

A well-differentiated (WHO grade II), diffusely infiltrating neuroglial tumor, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). (Adapted from WHO) [from NCI]

MedGen UID:
155550
Concept ID:
C0751396
Neoplastic Process
3.

Weight loss

A reduction in total body weight. [from NCI]

MedGen UID:
853198
Concept ID:
C1262477
Finding; Finding
4.

Epithelial Neoplasm

A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas. [from NCI]

MedGen UID:
277963
Concept ID:
C1368683
Neoplastic Process
5.

Postoperative vomiting

MedGen UID:
101050
Concept ID:
C0520905
Sign or Symptom
6.

Vomiting

Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic contractions. [from HPO]

MedGen UID:
12124
Concept ID:
C0042963
Sign or Symptom
7.

Nausea

A sensation of unease in the stomach together with an urge to vomit. [from HPO]

MedGen UID:
10196
Concept ID:
C0027497
Sign or Symptom
8.

Hydrocephalus

Autosomal recessive nonsyndromic hydrocephalus is characterized by onset in utero of enlarged ventricles due to a disturbance of cerebrospinal fluid accumulation. Affected individuals may have neurologic impairment (summary by Drielsma et al., 2012). Hydrocephalus can also be caused by Arnold-Chiari malformation, atresia of foramen of Magendie, stenosis of aqueduct of Sylvius (307000), toxoplasmosis, hydranencephaly, etc. Furthermore, it develops in infancy or childhood in achondroplasia (100800) and in Hurler disease (607014). Genetic Heterogeneity of Congenital Hydrocephalus See also autosomal recessive HYC2 (615219), caused by mutation in the MPDZ gene (603785) on chromosome 9p. An X-linked form (307000) is caused by mutation in the L1CAM gene on (308840) on chromosome Xq28. [from GTR]

MedGen UID:
9335
Concept ID:
C0020255
Disease or Syndrome
9.

Anorexia

A lack or loss of appetite for food (as a medical condition). [from HPO]

MedGen UID:
315
Concept ID:
C0003123
Disease or Syndrome; Finding
10.

Increased head circumference

MedGen UID:
909477
Concept ID:
C4083076
Finding
11.

Macrocephaly

MedGen UID:
851886
Concept ID:
CN233365
Finding
12.

Macrocephaly

Macrocephaly refers to an abnormally enlarged head inclusive of the scalp, cranial bones, and intracranial contents. Macrocephaly may be due to megalencephaly (true enlargement of the brain parenchyma), and the 2 terms are often used interchangeably in the genetic literature (reviews by Olney, 2007 and Williams et al., 2008). Autosomal recessive macrocephaly/megalencephaly syndrome is characterized by an enlarged cranium apparent at birth or in early childhood. Affected individuals have intellectual disability and may have dysmorphic facial features resulting from the macrocephaly (summary by Alfaiz et al., 2014). [from GTR]

MedGen UID:
745757
Concept ID:
C2243051
Disease or Syndrome; Finding
13.

Right

Being located on the right side of the body. [from HPO]

MedGen UID:
619189
Concept ID:
C0444532
Spatial Concept
14.

Resonance

MedGen UID:
534094
Concept ID:
C0231881
Finding
15.

Hydrocephalus

MedGen UID:
369747
Concept ID:
C1963137
Pathologic Function
16.

Staining

MedGen UID:
352872
Concept ID:
C1704680
Finding
17.

Proliferation

MedGen UID:
137720
Concept ID:
C0334094
Pathologic Function
18.

Mass of body structure

A benign or malignant pathologic structure in any part of the body, resulting from a neoplastic accumulation of cells, inflammatory cells, or cystic changes. [from NCI]

MedGen UID:
108287
Concept ID:
C0577559
Finding
19.

Undifferentiated illness: Vague ill health

A feeling of general discomfort or uneasiness, an out-of-sorts feeling.(CDC Glossary) [from NCI]

MedGen UID:
65412
Concept ID:
C0231218
Sign or Symptom
20.

Megalencephaly

A congenital abnormality in which the occipitofrontal circumference is greater than two standard deviations above the mean for a given age. It is associated with HYDROCEPHALUS; SUBDURAL EFFUSION; ARACHNOID CYSTS; or is part of a genetic condition (e.g., ALEXANDER DISEASE; SOTOS SYNDROME). [from MeSH]

MedGen UID:
65141
Concept ID:
C0221355
Congenital Abnormality; Finding
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