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Items: 3

1.

Dexamethasone

A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. (NCI04) [from NCI]

MedGen UID:
8344
Concept ID:
C0011777
Organic Chemical; Pharmacologic Substance
2.

Suppression

MedGen UID:
526147
Concept ID:
C0221103
Pathologic Function
3.

Hydrocortisone

A synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. (NCI04) [from NCI]

MedGen UID:
9337
Concept ID:
C0020268
Hormone; Organic Chemical; Pharmacologic Substance
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