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Items: 1 to 20 of 22

1.

Tyrosine

A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. [from MeSH]

MedGen UID:
21746
Concept ID:
C0041485
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
2.

Urokinase

A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES. [from MeSH]

MedGen UID:
21790
Concept ID:
C0042071
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
3.

Plasminogen

Plasminogen (810 aa, ~91 kDa) is encoded by the human PLG gene. This protein is involved in fibrinolysis, platelet activation and tissue remodeling. [from NCI]

MedGen UID:
10793
Concept ID:
C0032140
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
4.

Process

MedGen UID:
923307
Concept ID:
C1951340
Pharmacologic Substance
5.

Decreasing

MedGen UID:
617794
Concept ID:
C0442797
Finding
6.

Furriers lung

MedGen UID:
538594
Concept ID:
C0264476
Disease or Syndrome
7.

Coffee-workers lung

MedGen UID:
538589
Concept ID:
C0264468
Disease or Syndrome
8.

Cheese-washers lung

MedGen UID:
507549
Concept ID:
C0007969
Disease or Syndrome
9.

Dephosphorylation

The catalyzed removal of phosphate groups from biological molecules, by phosphatases. [from NCI]

MedGen UID:
463624
Concept ID:
C3160734
Molecular Function
10.

Proliferation

MedGen UID:
137720
Concept ID:
C0334094
Pathologic Function
11.

Heterogeneous

The presence of apparently similar characters for which the genetic evidence indicates that different genes or different genetic mechanisms are involved in different pedigrees. In clinical settings genetic heterogeneity refers to the presence of a variety of genetic defects which cause the same disease, often due to mutations at different loci on the same gene, a finding common to many human diseases including ALZHEIMER DISEASE; CYSTIC FIBROSIS; LIPOPROTEIN LIPASE DEFICIENCY, FAMILIAL; and POLYCYSTIC KIDNEY DISEASES. (Rieger, et al., Glossary of Genetics: Classical and Molecular, 5th ed; Segen, Dictionary of Modern Medicine, 1992) [from MeSH]

MedGen UID:
67020
Concept ID:
C0242960
Organism Attribute
12.

Plasminogen activator

A family of serine proteases that catalyze the proteolytic conversion of plasminogen to plasmin. [from NCI]

MedGen UID:
18508
Concept ID:
C0032144
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
13.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
14.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
15.

Abbokinase

MedGen UID:
148791
Concept ID:
C0701941
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
16.

Renokinase

MedGen UID:
147293
Concept ID:
C0701940
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
17.

Protease preparation

A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule. [from NCI]

MedGen UID:
45389
Concept ID:
C0030946
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
18.

Protein binding

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. [from MeSH]

MedGen UID:
18704
Concept ID:
C0033618
Molecular Function
19.

Enzyme inhibitor

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. [from MeSH]

MedGen UID:
8652
Concept ID:
C0014432
Pharmacologic Substance
20.

Electrolyte

Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed) [from MeSH]

MedGen UID:
3997
Concept ID:
C0013832
Inorganic Chemical; Pharmacologic Substance
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