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Items: 1 to 20 of 32

1.

Inflammation

A localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
2.

Methacholine

parasympathomimetic cholinergic agonist with predominantly muscarinic effects. [from CRISP]

MedGen UID:
109421
Concept ID:
C0600370
Organic Chemical; Pharmacologic Substance
3.

Up-Regulation (Physiology)

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. [from MeSH]

MedGen UID:
12003
Concept ID:
C0041904
Molecular Function
4.

Furriers lung

MedGen UID:
538594
Concept ID:
C0264476
Disease or Syndrome
5.

Coffee-workers lung

MedGen UID:
538589
Concept ID:
C0264468
Disease or Syndrome
6.

Cheese-washers lung

MedGen UID:
507549
Concept ID:
C0007969
Disease or Syndrome
7.

Ameliorated by

Weakened or thinned. Attenuated strains of disease-causing bacteria and viruses are often used as vaccines. The weakened strains are used as vaccines because they stimulate a protective immune response while causing no disease or only mild disease in the person receiving the vaccine. [from NCI_NCI-GLOSS]

MedGen UID:
83049
Concept ID:
C0332161
Qualitative Concept
8.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
9.

Provokit

MedGen UID:
295901
Concept ID:
C1563839
Organic Chemical; Pharmacologic Substance
10.

Provocholine

MedGen UID:
196304
Concept ID:
C0722884
Indicator, Reagent, or Diagnostic Aid; Organic Chemical; Pharmacologic Substance
11.

Prostenon

MedGen UID:
152085
Concept ID:
C0699578
Hormone; Organic Chemical; Pharmacologic Substance
12.

Acetyl-beta-methylcholine

MedGen UID:
99798
Concept ID:
C0524770
Organic Chemical; Pharmacologic Substance
13.

Mediator of inflammation

The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC). [from MeSH]

MedGen UID:
66209
Concept ID:
C0243042
Pharmacologic Substance
14.

Serpin

Irreversible serine proteinase inhibitors that exert their action on peptidases. Serpins can be localized inside, or outside of the cell, and are found in all groups of organisms with the exception of fungi. In human plasma, serpins represent approximately 2% of the total protein present. [from NCI]

MedGen UID:
48634
Concept ID:
C0036764
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
15.

Mecholyl

MedGen UID:
42547
Concept ID:
C0079810
Organic Chemical; Pharmacologic Substance
16.

Bronchial Hyperreactivity

Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory. [from MeSH]

MedGen UID:
38799
Concept ID:
C0085129
Disease or Syndrome
17.

Methacholine chloride

A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116) [from MeSH]

MedGen UID:
36342
Concept ID:
C0079829
Indicator, Reagent, or Diagnostic Aid; Organic Chemical; Pharmacologic Substance
18.

Respiratory Tract Diseases

Diseases involving the RESPIRATORY SYSTEM. [from MeSH]

MedGen UID:
19750
Concept ID:
C0035242
Disease or Syndrome
19.

Prostaglandins

group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway; extremely potent mediators of a diverse group of physiological processes. [from CRISP]

MedGen UID:
18692
Concept ID:
C0033554
Hormone; Organic Chemical; Pharmacologic Substance
20.

Abnormality of the bronchi

The bronchi are two tubes that branch off the trachea, or windpipe. The bronchi carry air to your lungs. The most common problem with the bronchi is bronchitis, an inflammation of the tubes. Bronchitis can be acute or chronic. Other problems include. -Bronchiectasis, a condition in which damage to the airways causes them to widen and become flabby and scarred. -Exercise-induced bronchospasm, which happens when the airways shrink while you are exercising. -Bronchiolitis, an inflammation of the small airways that branch off from the bronchi. -Bronchopulmonary dysplasia, a condition affecting infants. Treatment of bronchial disorders depends on the cause.  [from MedlinePlus]

MedGen UID:
14233
Concept ID:
C0006261
Disease or Syndrome
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