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Items: 19

1.

Leukemia

MedGen UID:
9725
Concept ID:
C0023418
Neoplastic Process
2.

Mutagenesis

Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS. [from MeSH]

MedGen UID:
86969
Concept ID:
C0079866
Molecular Function
3.

Process

MedGen UID:
923307
Concept ID:
C1951340
Pharmacologic Substance
4.

Growth arrest

MedGen UID:
569472
Concept ID:
C0333951
Pathologic Function
5.

Acute lymphoblastic leukemia

MedGen UID:
505958
Concept ID:
CN005851
Finding
6.

T-cell acute lymphoblastic leukemia

MedGen UID:
368378
Concept ID:
C1961099
Neoplastic Process
7.

Acute

Sudden appearance of disease manifestations over a short period of time. [from HPO]

MedGen UID:
61381
Concept ID:
C0205178
Temporal Concept
8.

Acute lymphoid leukemia

Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a subtype of acute leukemia, a cancer of the white blood cells. Somatically acquired mutations in several genes have been identified in ALL lymphoblasts, cells in the early stages of differentiation. Germline variation in certain genes may also predispose to susceptibility to ALL (Trevino et al., 2009). Genetic Heterogeneity of Acute Lymphoblastic Leukemia A susceptibility locus for acute lymphoblastic leukemia (ALL1) has been mapped to chromosome 10q21. See also ALL2 (613067), which has been mapped to chromosome 7p12.2; and ALL3 (615545), which is caused by mutation in the PAX5 gene (167414) on chromosome 9p. [from OMIM]

MedGen UID:
7317
Concept ID:
C0023449
Neoplastic Process
9.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
10.

Lymphatism

MedGen UID:
141817
Concept ID:
C0524631
Disease or Syndrome
11.

Protease preparation

A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule. [from NCI]

MedGen UID:
45389
Concept ID:
C0030946
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
12.

Abnormality of the lymphatic system

MedGen UID:
9829
Concept ID:
C0024228
Disease or Syndrome
13.

Lymphoid leukemia

MedGen UID:
9728
Concept ID:
C0023448
Neoplastic Process
14.

Enzyme inhibitor

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. [from MeSH]

MedGen UID:
8652
Concept ID:
C0014432
Pharmacologic Substance
15.

Immunoproliferative disorder

Disorders characterized by abnormal proliferation of primary cells of the immune system or by excessive production of immunoglobulins. [from MeSH]

MedGen UID:
7038
Concept ID:
C0021070
Neoplastic Process
16.

Hemic and Lymphatic Diseases

Hematologic diseases and diseases of the lymphatic system collectively. Hemic diseases include disorders involving the formed elements (e.g., ERYTHROCYTE AGGREGATION, INTRAVASCULAR) and chemical components (e.g., BLOOD PROTEIN DISORDERS); lymphatic diseases include disorders relating to lymph, lymph nodes, and lymphocytes. [from MeSH]

MedGen UID:
6780
Concept ID:
C0018981
Disease or Syndrome
17.

Lymphoproliferative disorder

MedGen UID:
6162
Concept ID:
C0024314
Neoplastic Process
18.

Leukemia, T Cell

A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood. [from MeSH]

MedGen UID:
6064
Concept ID:
C0023492
Neoplastic Process
19.

Disorder of immune system

A disorder resulting from an abnormality in the immune system. [from NCI]

MedGen UID:
5759
Concept ID:
C0021053
Disease or Syndrome
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