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Items: 1 to 20 of 29

1.

lopinavir

An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A. [from MeSH]

MedGen UID:
145897
Concept ID:
C0674432
Organic Chemical; Pharmacologic Substance
2.

Ritonavir

A peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cytochrome P450. [from NCI]

MedGen UID:
132886
Concept ID:
C0292818
Organic Chemical; Pharmacologic Substance
3.

Lopinavir+ritonavir

A combination of the drugs ritonavir and lopinavir. It is used to treat infection with HIV (the virus that causes AIDS). It is also being studied in the treatment of some types of cancer. Lopinavir/ritonavir blocks the ability of HIV to make copies of itself and may help other anticancer drugs work better or may block the growth of cancer cells. Ritonavir blocks the breakdown of lopinavir. Lopinavir/ritonavir is a type of anti-HIV agent and a type of protease inhibitor. [from NCI_NCI-GLOSS]

MedGen UID:
215250
Concept ID:
C0939237
Pharmacologic Substance
4.

Tenofovir disoproxil fumarate

A pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribed to treat HIV and chronic hepatitis B virus (HBV) in adults. [from NCI]

MedGen UID:
204740
Concept ID:
C1099776
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
5.

Tenofovir disoproxil

MedGen UID:
192561
Concept ID:
C0963398
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
6.

emtricitabine

A deoxycytidine analog and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B viruses. It is used to treat HIV INFECTIONS. [from MeSH]

MedGen UID:
178568
Concept ID:
C0909839
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
7.

Tenofovir

An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone. [from MeSH]

MedGen UID:
94499
Concept ID:
C0384228
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
8.

Diarrhea

What is diarrhea? Diarrhea is loose, watery stools (bowel movements). You have diarrhea if you have loose stools three or more times in one day. Acute diarrhea is diarrhea that lasts a short time. It is a common problem. It usually lasts about one or two days, but it may last longer. Then it goes away on its own. Diarrhea lasting more than a few days may be a sign of a more serious problem. Chronic diarrhea -- diarrhea that lasts at least four weeks -- can be a symptom of a chronic disease. Chronic diarrhea symptoms may be continual, or they may come and go. Who gets diarrhea? People of all ages can get diarrhea. On average, adults In the United States have acute diarrhea once a year. Young children have it an average of twice a year. People who visit developing countries are at risk for traveler's diarrhea. It is caused by consuming contaminated food or water. What causes diarrhea? The most common causes of diarrhea include. -Bacteria from contaminated food or water. -Viruses such as the flu, norovirus, or rotavirus . Rotavirus is the most common cause of acute diarrhea in children. -Parasites, which are tiny organisms found in contaminated food or water. -Medicines such as antibiotics, cancer drugs, and antacids that contain magnesium. -Food intolerances and sensitivities, which are problems digesting certain ingredients or foods. An example is lactose intolerance. -Diseases that affect the stomach, small intestine, or colon, such as Crohn's disease. -Problems with how the colon functions, such as irritable bowel syndrome. Some people also get diarrhea after stomach surgery, because sometimes the surgeries can cause food to move through your digestive system more quickly. Sometimes no cause can be found. If your diarrhea goes away within a few days, finding the cause is usually not necessary. What other symptoms might I have with diarrhea? Other possible symptoms of diarrhea include. -Cramps or pain in the abdomen. -An urgent need to use the bathroom. -Loss of bowel control. If a virus or bacteria is the cause of your diarrhea, you may also have a fever, chills, and bloody stools. Diarrhea can cause dehydration, which means that your body does not have enough fluid to work properly. Dehydration can be serious, especially for children, older adults, and people with weakened immune systems. When should I see a doctor for diarrhea? Although it is usually not harmful, diarrhea can become dangerous or signal a more serious problem. Contact your health care provider if you have. -Signs of dehydration. -Diarrhea for more than 2 days, if you are an adult. For children, contact the provider if it lasts more than 24 hours. -Severe pain in your abdomen or rectum (for adults). -A fever of 102 degrees or higher. -Stools containing blood or pus. -Stools that are black and tarry. If children have diarrhea, parents or caregivers should not hesitate to call a health care provider. Diarrhea can be especially dangerous in newborns and infants. How is the cause of diarrhea diagnosed? To find the cause of diarrhea, your health care provider may. -Do a physical exam. -Ask about any medicines you are taking. -Test your stool or blood to look for bacteria, parasites, or other signs of disease or infection. -Ask you to stop eating certain foods to see whether your diarrhea goes away. If you have chronic diarrhea, your health care provider may perform other tests to look for signs of disease. What are the treatments for diarrhea? Diarrhea is treated by replacing lost fluids and electrolytes to prevent dehydration. Depending on the cause of the problem, you may need medicines to stop the diarrhea or treat an infection. Adults with diarrhea should drink water, fruit juices, sports drinks, sodas without caffeine, and salty broths. As your symptoms improve, you can eat soft, bland food. Children with diarrhea should be given oral rehydration solutions to replace lost fluids and electrolytes. Can diarrhea be prevented? Two types of diarrhea can be prevented - rotavirus diarrhea and traveler's diarrhea. There are vaccines for rotavirus. They are given to babies in two or three doses. You can help prevent traveler's diarrhea by being careful about what you eat and drink when you are in developing countries:. -Use only bottled or purified water for drinking, making ice cubes, and brushing your teeth. -If you do use tap water, boil it or use iodine tablets. -Make sure that the cooked food you eat is fully cooked and served hot. -Avoid unwashed or unpeeled raw fruits and vegetables. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. [from MedlinePlus]

MedGen UID:
8360
Concept ID:
C0011991
Sign or Symptom
9.

Fumarate

MedGen UID:
526117
Concept ID:
C0220833
Organic Chemical; Pharmacologic Substance
10.

Moderate

Having a medium degree of severity. For quantitative traits, a deviation of between three and four standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
525853
Concept ID:
C0205081
Qualitative Concept
11.

Discontinued

To stop or end, permanently or temporarily. [from NCI]

MedGen UID:
303183
Concept ID:
C1444662
Finding
12.

Adverse event

unintended negative effect of treatments [from CHV]

MedGen UID:
209094
Concept ID:
C0877248
Pathologic Function
13.

Severe

Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
104640
Concept ID:
C0205082
Qualitative Concept
14.

Hiv

Infection caused by the human immunodeficiency virus. [from NCI_NICHD]

MedGen UID:
5583
Concept ID:
C0019693
Disease or Syndrome
15.

A-157378.0

MedGen UID:
205108
Concept ID:
C1110556
Organic Chemical; Pharmacologic Substance
16.

Norvir

MedGen UID:
195697
Concept ID:
C0678152
Organic Chemical; Pharmacologic Substance
17.

Viral disease

Viruses are capsules with genetic material inside. They are very tiny, much smaller than bacteria. Viruses cause familiar infectious diseases such as the common cold, flu and warts. They also cause severe illnesses such as HIV/AIDS, smallpox and hemorrhagic fevers. . Viruses are like hijackers. They invade living, normal cells and use those cells to multiply and produce other viruses like themselves. This eventually kills the cells, which can make you sick. Viral infections are hard to treat because viruses live inside your body's cells. They are protected from medicines, which usually move through your bloodstream. Antibiotics do not work for viral infections. There are a few antiviral medicines available. Vaccines can help prevent you from getting many viral diseases. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
53027
Concept ID:
C0042769
Disease or Syndrome
18.

Sexually Transmitted Diseases, Viral

Viral diseases which are transmitted or propagated by sexual conduct. [from MeSH]

MedGen UID:
48646
Concept ID:
C0036918
Disease or Syndrome
19.

Disease due to Retroviridae

Virus diseases caused by the RETROVIRIDAE. [from MeSH]

MedGen UID:
48440
Concept ID:
C0035369
Disease or Syndrome
20.

Disease due to Lentivirus

Virus diseases caused by the Lentivirus genus. They are multi-organ diseases characterized by long incubation periods and persistent infection. [from MeSH]

MedGen UID:
38233
Concept ID:
C0079680
Disease or Syndrome
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