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Items: 6

1.

Tenosynovial Giant Cell Tumor

A tumor usually arising in the synovium of joints, bursa or tendon sheath. It is characterized by the presence of mononuclear cells, multinucleated osteoclast-like giant cells, hemosiderin-laden macrophages, foam cells, and an inflammatory infiltrate. According to the growth pattern, it is classified as localized or diffuse. [from NCI]

MedGen UID:
232927
Concept ID:
C1318543
Neoplastic Process
2.

Giant cell tumor of bone

A benign but locally aggressive tumor that arises from the bone and is composed of mononuclear cells admixed with macrophages and osteoclast-like giant cells. It usually arises from the ends of long bones or the vertebrae. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint. [from NCI]

MedGen UID:
64624
Concept ID:
C0206638
Neoplastic Process
3.

Synovitis

Inflammation of a synovial membrane. [from NCI]

MedGen UID:
21051
Concept ID:
C0039103
Disease or Syndrome
4.

Giant cell tumor of bone

MedGen UID:
799512
Concept ID:
CN204745
Disease or Syndrome
5.

Tenosynovial Giant Cell Tumor, Diffuse Type

A locally aggressive, diffusely infiltrating tumor, arising in the tendon sheath. It is composed of synovial-like mononuclear cells, hemosiderin-laden macrophages, foam cells, and inflammatory cells. Multinucleated osteoclast-like giant cells are usually present, although in a minority of cases they may be absent or rare. It predominantly affects young adults. Symptoms include joint swelling, pain, and joint effusion. [from NCI]

MedGen UID:
11691
Concept ID:
C0039106
Neoplastic Process
6.

Giant cell tumor

A benign, intermediate, or malignant neoplasm characterized by the presence of neoplastic giant cells. [from NCI]

MedGen UID:
6598
Concept ID:
C0017525
Neoplastic Process
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