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Items: 17

1.

Gemfibrozil

A fibric acid derivative with hypolipidemic effects. Gemfibrozil interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. This enhances triglyceride-rich lipoprotein clearance and reduces the expression of apolipoprotein C-III (apoC-III). The reduction in hepatic production of apoC-III results in subsequent reduction of serum levels of very-low-density-lipoprotein cholesterol (VLDL-C). In addition, gemfibrozil-mediated PPARalpha stimulation of apoA-I and apoA-II expression results in an increase in high-density lipoprotein cholesterol (HDL-C). [from NCI]

MedGen UID:
8977
Concept ID:
C0017245
Organic Chemical; Pharmacologic Substance
2.

Trialmin

MedGen UID:
339186
Concept ID:
C1567613
Organic Chemical; Pharmacologic Substance
3.

Nu-Gemfibrozil

MedGen UID:
339185
Concept ID:
C1567608
Organic Chemical; Pharmacologic Substance
4.

Jezil

MedGen UID:
339168
Concept ID:
C1567536
Organic Chemical; Pharmacologic Substance
5.

Bolutol

MedGen UID:
339165
Concept ID:
C1567524
Organic Chemical; Pharmacologic Substance
6.

PMS-Gemfibrozil

MedGen UID:
298070
Concept ID:
C1567610
Organic Chemical; Pharmacologic Substance
7.

Novo-Gemfibrozil

MedGen UID:
298047
Concept ID:
C1567540
Organic Chemical; Pharmacologic Substance
8.

Gen-Gemfibrozil

MedGen UID:
298046
Concept ID:
C1567533
Organic Chemical; Pharmacologic Substance
9.

Gemhexal

MedGen UID:
298045
Concept ID:
C1567532
Organic Chemical; Pharmacologic Substance
10.

Decrelip

MedGen UID:
298040
Concept ID:
C1567527
Organic Chemical; Pharmacologic Substance
11.

Pilder

MedGen UID:
292654
Concept ID:
C1567609
Organic Chemical; Pharmacologic Substance
12.

Ausgem

MedGen UID:
292634
Concept ID:
C1567523
Organic Chemical; Pharmacologic Substance
13.

Litarek

MedGen UID:
291362
Concept ID:
C1567539
Organic Chemical; Pharmacologic Substance
14.

Lipazil

MedGen UID:
291360
Concept ID:
C1567537
Organic Chemical; Pharmacologic Substance
15.

Apo-Gemfibrozil

MedGen UID:
291359
Concept ID:
C1567522
Organic Chemical; Pharmacologic Substance
16.

C1-719

MedGen UID:
149210
Concept ID:
C0733860
Organic Chemical; Pharmacologic Substance
17.

Lopid

MedGen UID:
147080
Concept ID:
C0700003
Organic Chemical; Pharmacologic Substance
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