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Items: 1 to 20 of 30

1.

Dopamine

A monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1 and beta-1 adrenergic receptors. Mediated through myocardial beta-1 adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1 adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output. [from NCI]

MedGen UID:
41644
Concept ID:
C0013030
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
2.

Aggressive behavior

A verbal or physical act of hostility. [from NCI]

MedGen UID:
1375
Concept ID:
C0001807
Individual Behavior
3.

Brain-Derived Neurotrophic Factor

Brain-derived neurotrophic factor (247 aa, ~28 kDa) is encoded by the human BDNF gene. This protein plays a role in both the development of the nervous system and neuronal survival. [from NCI]

MedGen UID:
760637
Concept ID:
C3486709
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
4.

Aggressive behavior

Aggressive behavior can denote verbal aggression, physical aggression against objects, physical aggression against people, and may also include aggression towards oneself. [from HPO]

MedGen UID:
504570
Concept ID:
CN000675
Finding
5.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
6.

Acute

Sudden appearance of disease manifestations over a short period of time. [from HPO]

MedGen UID:
61381
Concept ID:
C0205178
Temporal Concept
7.

Stress

The negative mental, emotional, and physical reactions that occur when environmental stressors are perceived as exceeding the individual's adaptive capacities. [from NCI]

MedGen UID:
20971
Concept ID:
C0038435
Finding
8.

Antidepressant

A pharmacological agent that acts on neurotransmitter signaling pathways to alleviate the symptoms of depression. [from NCI]

MedGen UID:
1588
Concept ID:
C0003289
Pharmacologic Substance
9.

Imizin

MedGen UID:
906682
Concept ID:
C4082435
Organic Chemical; Pharmacologic Substance
10.

Sarafem

MedGen UID:
306390
Concept ID:
C1692877
Organic Chemical; Pharmacologic Substance
11.

Lilly-110140

MedGen UID:
154243
Concept ID:
C0543453
Organic Chemical; Pharmacologic Substance
12.

Melipramine

MedGen UID:
148754
Concept ID:
C0701353
Organic Chemical; Pharmacologic Substance
13.

Intropin

MedGen UID:
147406
Concept ID:
C0721081
Organic Chemical; Pharmacologic Substance
14.

Pryleugan

MedGen UID:
147253
Concept ID:
C0701354
Organic Chemical; Pharmacologic Substance
15.

Prozac

MedGen UID:
58088
Concept ID:
C0162373
Organic Chemical; Pharmacologic Substance
16.

Psychotherapeutic agent

A classification of medication that acts on the central nervous system, affecting brain function, level of consciousness, mood, emotions, and behavior. [from NCI]

MedGen UID:
46201
Concept ID:
C0033978
Pharmacologic Substance
17.

imipramine

A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04) [from NCI]

MedGen UID:
43829
Concept ID:
C0020934
Organic Chemical; Pharmacologic Substance
18.

Fluoxetine

The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants. [from MeSH]

MedGen UID:
42053
Concept ID:
C0016365
Organic Chemical; Pharmacologic Substance
19.

Thymoanaleptics

MedGen UID:
21538
Concept ID:
C0040094
Pharmacologic Substance
20.

Psychological stress

Stress wherein emotional factors predominate. [from MeSH]

MedGen UID:
21349
Concept ID:
C0038443
Mental or Behavioral Dysfunction
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