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Items: 7

1.

Metformin

A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289) [from MeSH]

MedGen UID:
7578
Concept ID:
C0025598
Organic Chemical; Pharmacologic Substance
2.

Acidosis

A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up. [from MeSH]

MedGen UID:
1296
Concept ID:
C0001122
Pathologic Function
3.

Metformin

MedGen UID:
1095213
Concept ID:
CN425044
Pharmacologic Substance
4.

Prolonged

Applied to an abnormality whose duration is extended over a longer period of time than is expected or usual (e.g., prolonged fever lasts longer than one usually sees with an infection). [from HPO]

MedGen UID:
615082
Concept ID:
C0439590
Temporal Concept
5.

Severe lactic acidosis

A severe form of lactic acidemia. [from HPO]

MedGen UID:
374223
Concept ID:
C1839436
Finding
6.

Severe

Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
104640
Concept ID:
C0205082
Qualitative Concept
7.

Lactic acidosis

Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE. [from MeSH]

MedGen UID:
1717
Concept ID:
C0001125
Disease or Syndrome
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