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Items: 1 to 20 of 30

1.

Aspergillosis

Aspergillosis is a disease caused by a fungus (or mold) called Aspergillus. The fungus is very common in both indoors and outdoors. Most people breathe in the spores of the fungus every day without being affected. But some people get the disease. It usually occurs in people with lung diseases or weakened immune systems. There are different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA). Symptoms of ABPA include wheezing and coughing. ABPA can affect healthy people but it is most common in people with asthma or cystic fibrosis. Another kind is invasive aspergillosis, which damages tissues in the body. It usually affects the lungs. Sometimes it can also cause infection in other organs and spread throughout the body. It affects people who have immune system problems, such as people who have had a transplant, are taking high doses of steroids, or getting chemotherapy for some cancers. Your doctor might do a variety of tests to make the diagnosis, including a chest x-ray, CT scan of the lungs, and an examination of tissues for signs of the fungus. Treatment is with antifungal drugs. If you have ABPA, you may also take steroids. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
13939
Concept ID:
C0004030
Disease or Syndrome
2.

Diagnosis

The process of identifying a disease, such as cancer, from its signs and symptoms. [from NCI]

MedGen UID:
8354
Concept ID:
C0011900
Finding
3.

Invasive aspergillosis

MedGen UID:
922866
Concept ID:
C0238013
Disease or Syndrome
4.

Voriconazole

A triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A. [from MeSH]

MedGen UID:
97944
Concept ID:
C0393080
Organic Chemical; Pharmacologic Substance
5.

Risk factor

Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury. [from NCI]

MedGen UID:
48477
Concept ID:
C0035648
Finding; Quantitative Concept
6.

Neutropenic disorder

An abnormal decrease in the number of neutrophils, a type of white blood cell. [from NCI]

MedGen UID:
18030
Concept ID:
C0027947
Disease or Syndrome; Finding
7.

Transplantation

MedGen UID:
881115
Concept ID:
CN236682
Disease or Syndrome
8.

Organ Transplantation

MedGen UID:
881071
Concept ID:
CN236669
Disease or Syndrome
9.

Infections

MedGen UID:
833099
Concept ID:
CN228891
Finding
10.

Prolonged

MedGen UID:
615082
Concept ID:
C0439590
Temporal Concept
11.

Life Threatening

A situation that imperils the existence of an entity. [from NCI]

MedGen UID:
415288
Concept ID:
C2826244
Finding
12.

Echinocandins

Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS. [from MeSH]

MedGen UID:
224778
Concept ID:
C1268551
Pharmacologic Substance
13.

Neutropenia

An abnormally low number of neutrophils in the peripheral blood. [from HPO]

MedGen UID:
163121
Concept ID:
C0853697
Finding
14.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
15.

Severe

Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
104640
Concept ID:
C0205082
Qualitative Concept
16.

Immunocompromised Host

A loss of any arm of immune functions resulting in potential or actual increase in infections. This state may be reached due to specific genetic lesions, syndromes with unidentified or polygenic causes, acquired deficits from other disease states, or as result of therapy for other diseases or conditions. [from NCI_NICHD]

MedGen UID:
39272
Concept ID:
C0085393
Finding
17.

Chronic granulomatous disease

A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern. [from MeSH]

MedGen UID:
5377
Concept ID:
C0018203
Disease or Syndrome
18.

Antifungal Agents

a drug that kills fungus [from CHV]

MedGen UID:
1594
Concept ID:
C0003308
Pharmacologic Substance
19.

AIDS

A disease caused by human immunodeficiency virus (HIV). People with acquired immunodeficiency syndrome are at an increased risk for developing certain cancers and for infections that usually occur only in individuals with a weak immune system. [from NCI]

MedGen UID:
99
Concept ID:
C0001175
Disease or Syndrome
20.

Hyalohyphomycosis

OPPORTUNISTIC INFECTIONS caused by a heterogeneous group of MITOSPORIC FUNGI with clear (hyalo-) HYPHAE in the host. Common causative agents include ACREMONIUM; ASPERGILLUS; CHRYSOSPORIUM; FUSARIUM; PAECILOMYCES; PENICILLIUM; PSEUDALLESCHERIA; SCEDOSPORIUM; and SCOPULARIOPSIS. Normally a dermatomycoses, it can become invasive in the IMMUNOCOMPROMISED HOST. [from MeSH]

MedGen UID:
452455
Concept ID:
C0343952
Disease or Syndrome
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