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Items: 3

1.

Mirtazapine

A synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity. Although its mechanism of action is unknown, mirtazapine enhances central adrenergic and serotonergic transmission, possibly by acting as an antagonist at central presynaptic alpha 2 adrenergic inhibitory autoreceptors and heteroreceptors. This agent is a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors. [from NCI]

MedGen UID:
25156
Concept ID:
C0049506
Organic Chemical; Pharmacologic Substance
2.

Phobic disorder

An anxiety disorder characterized by an intense, irrational fear of an object, activity, or situation. The individual seeks to avoid the object, activity, or situation. In adults, the individual recognizes that the fear is excessive or unreasonable. [from NCI]

MedGen UID:
83881
Concept ID:
C0349231
Mental or Behavioral Dysfunction
3.

Social phobia

An anxiety disorder characterized by an intense, irrational fear of one or more social or performance situations in which the individual believes that he or she will be scrutinized by others. Exposure to social situations immediately provokes an anxiety response. In adults, the social phobia is recognized as excessive or unreasonable. [from NCI]

MedGen UID:
19254
Concept ID:
C0031572
Mental or Behavioral Dysfunction
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