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Items: 3

1.

Palivizumab

A humanized monoclonal antibody against the fusion protein (F protein) of human respiratory syncytial virus (RSV), with prophylactic application in respiratory syncytial virus infections. RSV F protein, a small envelop glycoprotein, is not only required for cytopathic syncytia resulting from cell-to-cell fusion, but is also necessary for viral spreading and evading neutralizing antibody. Palivizumab neutralizes and inhibits fusion activity of RSV, thereby preventing syncytia formation. Administration of this antibody does not interfere with other immunizations. [from NCI]

MedGen UID:
151303
Concept ID:
C0672596
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
2.

Respiratory syncytial virus infection

Infection with the respiratory syncytial virus, an RNA virus of the genus Pneumovirus, in the family Paramyxoviridae, which is characterized by the formation of syncytia in tissue culture. It causes minor respiratory infection with rhinitis and cough in adults, but is capable of causing severe bronchitis and bronchopneumonia in young children. [from NCI]

MedGen UID:
48424
Concept ID:
C0035235
Disease or Syndrome
3.

Synagis

MedGen UID:
152535
Concept ID:
C0723567
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
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