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Items: 13

1.

Vaccinia

The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine. [from MeSH]

MedGen UID:
52964
Concept ID:
C0042214
Disease or Syndrome
2.

Smallpox

A condition that is caused by infection with Variola, and that is characterized by small, raised bumps. [from NCI]

MedGen UID:
20785
Concept ID:
C0037354
Disease or Syndrome
3.

Vaccine

Preparations containing substances with antigenic properties administered to activate the immune system, thereby inducing an immune response. [from NCI]

MedGen UID:
52963
Concept ID:
C0042210
Immunologic Factor; Pharmacologic Substance
4.

Smallpox vaccine

A live VACCINIA VIRUS vaccine of calf lymph or chick embryo origin, used for immunization against smallpox. It is now recommended only for laboratory workers exposed to smallpox virus. Certain countries continue to vaccinate those in the military service. Complications that result from smallpox vaccination include vaccinia, secondary bacterial infections, and encephalomyelitis. (Dorland, 28th ed) [from MeSH]

MedGen UID:
20786
Concept ID:
C0037355
Immunologic Factor; Pharmacologic Substance
5.

DNA Vaccine

DNA vaccines are used in vaccination in way that differs from those are designed to be inserted into germ line of vaccines. Therefore, this is a vaccine not a therapy for modifying genetic information (gene therapy). Direct innoculation of DNA vaccine causes expression of the recombinant DNA by cells in the inoculated host. This expression of the recombinant DNA produces protein of interest that promotes antibody, cytolytic T cell and protective immune responses. [from NCI]

MedGen UID:
138230
Concept ID:
C0376613
Immunologic Factor; Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
6.

Viral vaccine

Any vaccine preparation composed of a live, attenuated, inactivated, killed or recombinant virus. Administration of a viral vaccine is to provide prophylaxis against viral disease or used as a vehicle to treat cancers. [from NCI]

MedGen UID:
22655
Concept ID:
C0042742
Immunologic Factor; Pharmacologic Substance
7.

Vaccines, Synthetic

Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified. [from MeSH]

MedGen UID:
22601
Concept ID:
C0042213
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
8.

Artificial antigen

small synthetic peptides that mimic surface antigens of pathogens and are immunogenic. [from CRISP]

MedGen UID:
11692
Concept ID:
C0039115
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
9.

Vaccines, Recombinant

MedGen UID:
11144
Concept ID:
C0034862
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
10.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
11.

Interferon gamma

Interferon gamma (166 aa, ~19 kDa) is encoded by the human IFNG gene. This protein is involved in antiviral activity, macrophage activation, antiproliferative activity and immunopotentiation. [from NCI]

MedGen UID:
5846
Concept ID:
C0021745
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
12.

PRODUCTS BIOL

Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay. [from MeSH]

MedGen UID:
577
Concept ID:
C0005522
Biologically Active Substance; Pharmacologic Substance
13.

Alastrim

A orthopoxvirus that causes a milder clinical syndrome than smallpox. [from NCI]

MedGen UID:
1393
Concept ID:
C0001906
Disease or Syndrome
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