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1.

Vaccines

A Type of medicine that creates an immune protection without the recipient experiencing the disease.  [from HL7]

MedGen UID:
52963
Concept ID:
C0042210
Immunologic Factor; Pharmacologic Substance
2.

Autoimmune state

Process whereby the immune system reacts against the body's own tissues. Autoimmunity may produce or be caused by AUTOIMMUNE DISEASES. [from MeSH]

MedGen UID:
2136
Concept ID:
C0004368
Pathologic Function
3.

Autoimmunity

The occurrence of an immune reaction against the organism's own cells or tissues. [from HPO]

MedGen UID:
505423
Concept ID:
CN002679
Finding
4.

Autoimmune disease

Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. No one is sure what causes autoimmune diseases. They do tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases. There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting a diagnosis can be frustrating and stressful. Often, the first symptoms are fatigue, muscle aches and a low fever. The classic sign of an autoimmune disease is inflammation, which can cause redness, heat, pain and swelling. The diseases may also have flare-ups, when they get worse, and remissions, when symptoms get better or disappear. Treatment depends on the disease, but in most cases one important goal is to reduce inflammation. Sometimes doctors prescribe corticosteroids or other drugs that reduce your immune response.  [from MedlinePlus]

MedGen UID:
2135
Concept ID:
C0004364
Disease or Syndrome
5.

Molecular Mimicry

The structure of one molecule that imitates or simulates the structure of a different molecule. [from MeSH]

MedGen UID:
116705
Concept ID:
C0242943
Molecular Function
6.

tetanus toxoid vaccine, inactivated

A substance that is derived from the toxin released by the bacterium that causes the disease tetanus. It is used as a vaccine to prevent tetanus or to help boost the immune response to other vaccines. [from NCI_NCI-GLOSS]

MedGen UID:
81364
Concept ID:
C0305062
Amino Acid, Peptide, or Protein; Immunologic Factor; Organic Chemical; Pharmacologic Substance
7.

Thrombocytopenia

A reduction in the number of circulating thrombocytes. [from HPO]

MedGen UID:
52737
Concept ID:
C0040034
Disease or Syndrome; Finding
8.

Tetanus Toxoid

MedGen UID:
52680
Concept ID:
C0039619
Immunologic Factor; Organic Chemical; Pharmacologic Substance
9.

Tetanus

Tetanus is a serious illness caused by Clostridium bacteria. The bacteria live in soil, saliva, dust, and manure. The bacteria can enter the body through a deep cut, like those you might get from stepping on a nail, or through a burn. The infection causes painful tightening of the muscles, usually all over the body. It can lead to locking of the jaw. This makes it impossible to open your mouth or swallow. Tetanus is a medical emergency. You need to get treatment in a hospital. A vaccine can prevent tetanus. It is given as a part of routine childhood immunization. Adults should get a tetanus shot, or booster, every 10 years. If you get a bad cut or burn, see your doctor - you may need a booster. Immediate and proper wound care can prevent tetanus infection.  [from MedlinePlus]

MedGen UID:
21489
Concept ID:
C0039614
Disease or Syndrome
10.

Estrogens

A class of natural or synthetic hormones that binds to a cytoplasmic receptor and initiates translocation of the hormone-receptor complex to the nucleus of target cells of tissues rich in estrogen receptors, including the endometrium, myometrium, oviduct, vagina, fallopian tube, cervix, brain, liver, placenta, ovarian cells, Leydigs cells, kidney, prostate, pancreas, heart, and skin. (NCI) [from NCI]

MedGen UID:
8701
Concept ID:
C0014939
Hormone; Organic Chemical; Pharmacologic Substance; Steroid
11.

Measles

Measles is an infectious disease caused by a virus. It spreads easily from person to person. It causes a blotchy red rash. The rash often starts on the head and moves down the body. Other symptoms include. -Fever. -Cough. -Runny nose. -Conjunctivitis (pink eye). -Feeling achy and run down. -Tiny white spots inside the mouth. Sometimes measles can lead to serious problems. There is no treatment for measles, but the measles-mumps-rubella (MMR) vaccine can prevent it. German measles, also known as rubella, is a completely different illness. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
6252
Concept ID:
C0025007
Disease or Syndrome
12.

Diphtheria

Diphtheria is a serious bacterial infection. You can catch it from a person who has the infection and coughs or sneezes. You can also get infected by coming in contact with an object, such as a toy, that has bacteria on it. Diphtheria usually affects the nose and throat. Symptoms include. -Sore throat. -Swollen glands in the neck. -Fever. -Weakness. Your doctor will diagnose it based on your signs and symptoms and a lab test. Getting treatment for diphtheria quickly is important. If your doctor suspects that you have it, you'll start treatment before the lab tests come back. Treatment is with antibiotics. The diphtheria, pertussis, and tetanus (DPT) vaccine can prevent diphtheria, but its protection does not last forever. Children need another dose, or booster, at about age 12. Then, as adults, they should get a booster every 10 years. Diphtheria is very rare in the United States because of the vaccine. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
4334
Concept ID:
C0012546
Disease or Syndrome
13.

Guillain-Barre Syndrome, Familial

MedGen UID:
901636
Concept ID:
C4083008
Disease or Syndrome
14.

Infections

MedGen UID:
833099
Concept ID:
CN228891
Finding
15.

Autoimmune thrombocytopenia

An autoimmune coagulation disorder characterized by isolated thrombocytopenia (a platelet count <100,000/microL), in the absence of any underlying disorder that may be associated with thrombocytopenia. [from SNOMEDCT_US]

MedGen UID:
584986
Concept ID:
C0398650
Disease or Syndrome
16.

Mimicry

MedGen UID:
535387
Concept ID:
C0233577
Mental or Behavioral Dysfunction
17.

Thrombocytopenia

MedGen UID:
472158
Concept ID:
CN130080
Disease or Syndrome
18.

Cell Invasion

The movement of one cell type into an area normally occupied by a different cell type. [from NCI]

MedGen UID:
397081
Concept ID:
C2699153
Pathologic Function
19.

Guillain-Barre syndrome, familial

Guillain-Barre syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy characterized most commonly by symmetric limb weakness and loss of tendon reflexes. It is a putative autoimmune disorder presenting after an infectious illness, most commonly Campylobacter jejuni, a gram-negative bacterium that causes acute enteritis (Yuki and Tsujino, 1995; Koga et al., 2005). Approximately 1 in 1,000 individuals develops GBS after C. jejuni infection (Nachamkin, 2001). Although rare familial cases have been reported, GBS is considered to be a complex multifactorial disorder with both genetic and environmental factors rather than a disorder following simple mendelian inheritance (Geleijns et al., 2004). [from OMIM]

MedGen UID:
374775
Concept ID:
C1841700
Disease or Syndrome
20.

Acyl-CoA thioester hydrolase, long-chain, 1

MedGen UID:
351308
Concept ID:
C1865144
Amino Acid, Peptide, or Protein; Enzyme; Finding
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