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Items: 3

1.

Mirtazapine

A synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity. Although its mechanism of action is unknown, mirtazapine enhances central adrenergic and serotonergic transmission, possibly by acting as an antagonist at central presynaptic alpha 2 adrenergic inhibitory autoreceptors and heteroreceptors. This agent is a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors. [from NCI]

MedGen UID:
25156
Concept ID:
C0049506
Organic Chemical; Pharmacologic Substance
2.

Amphetamine

Chemical racemic free base or equal parts of enantiomers levoamphetamine and dextroamphetamine in their pure amine or salt forms. [from SNOMEDCT_US]

MedGen UID:
266
Concept ID:
C0002658
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
3.

Amphetamine dependence

MedGen UID:
68634
Concept ID:
C0236804
Mental or Behavioral Dysfunction
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