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Items: 1 to 20 of 33

1.

Testicular Germ Cell Tumor

A neoplasm arising from gonadal tissue within the testes. [from NCI_NICHD]

MedGen UID:
277809
Concept ID:
C1336708
Neoplastic Process
2.

Cisplatin

A drug used to treat many types of cancer. Cisplatin contains the metal platinum. It kills cancer cells by damaging their DNA and stopping them from dividing. Cisplatin is a type of alkylating agent. [from NCI_NCI-GLOSS]

MedGen UID:
40318
Concept ID:
C0008838
Inorganic Chemical; Pharmacologic Substance
3.

Germ cell tumor

MedGen UID:
798860
Concept ID:
CN204400
Disease or Syndrome
4.

Germ cell tumor of testis

MedGen UID:
798021
Concept ID:
CN204703
Disease or Syndrome
5.

Embryonal Carcinoma

A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595) [from MeSH]

MedGen UID:
61653
Concept ID:
C0206659
Neoplastic Process
6.

Germ cell tumor

A benign or malignant, gonadal or extragonadal neoplasm that originates from germ cells. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor. [from NCI]

MedGen UID:
60030
Concept ID:
C0205851
Neoplastic Process
7.

Malignant tumor of testis

Testicular germ cell tumors (TGCTs) affect 1 in 500 men and are the most common cancer in males aged 15 to 40 in western European populations. The incidence of TGCT rose dramatically during the 20th century. Known risk factors for TGCT include a history of undescended testis (UDT), testicular dysgenesis, infertility, previously diagnosed TGCT, and a family history of the disease. Brothers of men with TGCT have an 8- to 10-fold risk of developing TGCT, whereas the relative risk to fathers and sons is 4-fold. This familial relative risk is much higher than that for most other types of cancer (summary by Rapley et al., 2000). Genetic Heterogeneity of Testicular Germ Cell Tumors A locus for testicular germ cell tumors (TGCT1; 300228) has been identified on chromosome Xq27. [from OMIM]

MedGen UID:
56313
Concept ID:
C0153594
Neoplastic Process
8.

Oxygen

An element with atomic symbol O, atomic number 8, and atomic weight 16. [from NCI]

MedGen UID:
45267
Concept ID:
C0030054
Biologically Active Substance; Element, Ion, or Isotope; Pharmacologic Substance
9.

Embryonal neoplasm

new abnormal embryonic tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease. [from CRISP]

MedGen UID:
45034
Concept ID:
C0027654
Neoplastic Process
10.

IgE-mediated allergic disorder

Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability. [from MeSH]

MedGen UID:
43785
Concept ID:
C0020523
Pathologic Function
11.

Allergy

An allergy is a reaction by your immune system to something that does not bother most other people. People who have allergies often are sensitive to more than one thing. Substances that often cause reactions are. -Pollen. -Dust mites. -Mold spores. -Pet dander. -Food. -Insect stings. -Medicines. Normally, your immune system fights germs. It is your body's defense system. In most allergic reactions, however, it is responding to a false alarm. Genes and the environment probably both play a role. Allergies can cause a variety of symptoms such as a runny nose, sneezing, itching, rashes, swelling, or asthma. Allergies can range from minor to severe. Anaphylaxis is a severe reaction that can be life-threatening. Doctors use skin and blood tests to diagnose allergies. Treatments include medicines, allergy shots, and avoiding the substances that cause the reactions. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
9370
Concept ID:
C0020517
Pathologic Function
12.

Carcinoma

A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas (NCI Thesaurus). [from HPO]

MedGen UID:
2867
Concept ID:
C0007097
Neoplastic Process
13.

Carcinoma

MedGen UID:
910818
Concept ID:
CN241453
Finding
14.

cytotoxicity

The adverse effect of some iatrogenic therapies. It is an accepted side effect in radiation therapy where the desired effect is to kill rapidly growing tumor cells. In the killing of tumor cells, other cells that are rapidly growing e.g hair, mucous membranes are also killed. [from NCI]

MedGen UID:
108579
Concept ID:
C0596402
Cell or Molecular Dysfunction
15.

Fetal alcohol syndrome

Alcohol can harm your baby at any stage during a pregnancy. That includes the earliest stages before you even know you are pregnant. Drinking alcohol can cause a group of conditions called fetal alcohol spectrum disorders (FASDs). Effects can include physical and behavioral problems such as trouble with. -Learning and remembering. -Understanding and following directions. -Controlling emotions. -Communicating and socializing. -Daily life skills, such as feeding and bathing. Fetal alcohol syndrome is the most serious type of FASD. People with fetal alcohol syndrome have facial abnormalities, including wide-set and narrow eyes, growth problems and nervous system abnormalities. FASDs last a lifetime. There is no cure for FASDs. Treatments can help. These include medicines to help with some symptoms and behavior therapy. No one treatment is right for every child. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
8820
Concept ID:
C0015923
Disease or Syndrome
16.

Male Urogenital Diseases

Pathological processes of the male URINARY TRACT and the reproductive system (GENITALIA, MALE). [from MeSH]

MedGen UID:
318601
Concept ID:
C1720894
Disease or Syndrome
17.

Cancer, Embryonal

MedGen UID:
199639
Concept ID:
C0751364
Neoplastic Process
18.

Platinol

MedGen UID:
195927
Concept ID:
C0699666
Inorganic Chemical; Pharmacologic Substance
19.

NSC-119875

MedGen UID:
181696
Concept ID:
C0936226
Inorganic Chemical; Pharmacologic Substance
20.

Platino

MedGen UID:
152100
Concept ID:
C0699665
Inorganic Chemical; Pharmacologic Substance
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