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Items: 20

1.

Progesterone

A synthetic form of the endogenous hormone progesterone. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy. (NCI04) [from NCI]

MedGen UID:
18661
Concept ID:
C0033308
Hormone; Organic Chemical; Pharmacologic Substance
2.

Estradiol

A steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Typically esterified, estradiol derivatives are formulated for oral or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. [from NCI]

MedGen UID:
4551
Concept ID:
C0014912
Hormone; Organic Chemical; Pharmacologic Substance
3.

Invasion

The movement of one cell type into an area normally occupied by a different cell type. [from NCI]

MedGen UID:
397081
Concept ID:
C2699153
Pathologic Function
4.

Localized

Being confined or restricted to a particular location. [from HPO]

MedGen UID:
98236
Concept ID:
C0392752
Spatial Concept
5.

Lateral

Applies to an abnormality that is located farther from the median plane or midline of the body or of the referenced structure. [from HPO]

MedGen UID:
64373
Concept ID:
C0205093
Spatial Concept
6.

Aerodiol

MedGen UID:
365356
Concept ID:
C1951509
Hormone; Organic Chemical; Pharmacologic Substance
7.

Female Urogenital Diseases and Pregnancy Complications

Pathological processes of the female URINARY TRACT, the reproductive system (GENITALIA, FEMALE), and disorders related to PREGNANCY. [from MeSH]

MedGen UID:
318565
Concept ID:
C1720765
Disease or Syndrome
8.

Vivelle

MedGen UID:
196344
Concept ID:
C0724374
Hormone; Organic Chemical; Pharmacologic Substance
9.

Ovocylin

MedGen UID:
148487
Concept ID:
C0699359
Hormone; Organic Chemical; Pharmacologic Substance
10.

Estrace

MedGen UID:
148486
Concept ID:
C0699352
Hormone; Organic Chemical; Pharmacologic Substance
11.

Phenol

An antiseptic and disinfectant aromatic alcohol. [from MeSH]

MedGen UID:
74524
Concept ID:
C0070570
Organic Chemical; Pharmacologic Substance
12.

Pregnancy Complication

The co-occurrence of pregnancy and a disease. The disease may precede or follow conception and it may or may not have a deleterious effect on the pregnant woman or fetus. [from NCI]

MedGen UID:
46066
Concept ID:
C0032962
Disease or Syndrome
13.

Phenol and derivatives

Benzene derivatives that include one or more hydroxyl groups attached to the ring structure. [from MeSH]

MedGen UID:
45854
Concept ID:
C0031428
Organic Chemical; Pharmacologic Substance
14.

Non-steroidal estrogen preparation

Estrogens that are not steroids, but have a structural configuration resembling steroids and may mimic steroidal estrogen effect or bind to estrogen receptors. [from NCI]

MedGen UID:
41879
Concept ID:
C0014940
Hormone; Organic Chemical; Pharmacologic Substance
15.

Sex hormone

A class of steroid hormones that specifically binds to and activates androgen, progesterone or estrogen receptors. Sex steroids activate various signaling pathways involved in the development and maintenance of secondary sexual characteristics, reproductive processes, blood salt balance, response to stress, neuronal function and a number of metabolic processes. [from NCI]

MedGen UID:
19951
Concept ID:
C0036884
Hormone; Pharmacologic Substance
16.

Pregnancy

The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. [from NCI]

MedGen UID:
10895
Concept ID:
C0032961
Organism Function
17.

Estrogenic preparation

A class of natural or synthetic hormones that binds to a cytoplasmic receptor and initiates translocation of the hormone-receptor complex to the nucleus of target cells of tissues rich in estrogen receptors, including the endometrium, myometrium, oviduct, vagina, fallopian tube, cervix, brain, liver, placenta, ovarian cells, Leydigs cells, kidney, prostate, pancreas, heart, and skin. (NCI) [from NCI]

MedGen UID:
8701
Concept ID:
C0014939
Hormone; Organic Chemical; Pharmacologic Substance
18.

Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. [from MeSH]

MedGen UID:
6887
Concept ID:
C0019934
Pharmacologic Substance
19.

Estrogens, Synthetic

Compounds obtained by chemical synthesis which possess estrogenic activity, but differ in structure from naturally occurring estrogens. [from MeSH]

MedGen UID:
4558
Concept ID:
C0014941
Organic Chemical; Pharmacologic Substance
20.

Steroidal estrogen preparation

MedGen UID:
551234
Concept ID:
C0304770
Hormone; Organic Chemical; Pharmacologic Substance
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