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Items: 1 to 20 of 21

1.

Substance dependence

MedGen UID:
20989
Concept ID:
C0038580
Mental or Behavioral Dysfunction
2.

Dependence

The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence. [from NCI]

MedGen UID:
141006
Concept ID:
C0439857
Mental or Behavioral Dysfunction
3.

Psychoactive substance dependence

Drug dependence - replaced the term "drug addiction" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug. [from NCI]

MedGen UID:
307144
Concept ID:
C1510472
Mental or Behavioral Dysfunction
4.

Stimulant dependence

MedGen UID:
751384
Concept ID:
C2711618
Mental or Behavioral Dysfunction
5.

Stimulant

a chemical agent such as caffeine, that temporarily arouses or accelerates physical activity [from CHV]

MedGen UID:
551075
Concept ID:
C0304402
Pharmacologic Substance
6.

Moderate

Having a medium degree of severity. For quantitative traits, a deviation of between three and four standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
525853
Concept ID:
C0205081
Qualitative Concept
7.

Withdrawal

A social or emotional detachment, pathological retreat from objective reality, interpersonal contact and social involvement, as in some forms of schizophrenia, depression, or schizoid, avoidant, or schizotypal personality disorders. [from NCI]

MedGen UID:
442895
Concept ID:
C2825032
Mental or Behavioral Dysfunction
8.

Symptom

Subjective evidence of disease perceived by the patient. [from NCI]

MedGen UID:
306142
Concept ID:
C1457887
Sign or Symptom
9.

Severity

The intensity or degree of a manifestation. [from HPO]

MedGen UID:
101096
Concept ID:
C0522510
Qualitative Concept
10.

Marijuana

Any part of, or extract from, the female hemp plant Cannabis sativa. Marijuana contains cannabinoids, substances with hallucinogenic, psychoactive, and addictive properties. This agent has potential use for treating cancer pain and cachexia. (NCI04) [from NCI]

MedGen UID:
44288
Concept ID:
C0024808
Organic Chemical; Pharmacologic Substance
11.

Mucolipidosis II

An inherited lysosomal storage disease characterized by the presence of dense intracytoplasmic inclusions in mesenchymal cells, especially fibroblasts. Signs and symptoms include developmental delay, psychomotor deterioration, and growth failure. [from NCI]

MedGen UID:
43809
Concept ID:
C0020725
Disease or Syndrome
12.

Alcohol dependence

A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4) [from MeSH]

MedGen UID:
1801
Concept ID:
C0001973
Mental or Behavioral Dysfunction
13.

Alcohol

A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the position of the carbon atom with the attached hydroxyl group (i.e. primary alcohols are alcohols with the OH group attached to the primary carbon atom, C1). Uses include solvents, astringents, and anti-infective activity. [from NCI]

MedGen UID:
1400
Concept ID:
C0001975
Organic Chemical; Pharmacologic Substance
14.

Ethyl alcohol

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES. [from MeSH]

MedGen UID:
186
Concept ID:
C0001962
Organic Chemical; Pharmacologic Substance
15.

Diagnosis, Psychiatric

MedGen UID:
138165
Concept ID:
C0376338
Mental or Behavioral Dysfunction
16.

Substance-Related Disorder

A category of psychiatric disorders which include disorders related to the taking of a drug of abuse (including alcohol, prescribed medications and recreational drugs). [from NCI]

MedGen UID:
66746
Concept ID:
C0236969
Mental or Behavioral Dysfunction
17.

Abuse, Marijuana

Use of marijuana associated with abnormal psychological, social, and or occupational functioning. [from MeSH]

MedGen UID:
44289
Concept ID:
C0024809
Mental or Behavioral Dysfunction
18.

Substance Withdrawal Syndrome

A substance-specific organic brain syndrome that follows the discontinuation of administration or use, or reduction in intake of an addictive substance, e.g. opioids, barbiturates and alcohol; amphetamines or similarly acting sympathomimetics; cocaine; nicotine; sedatives, hypnotics, or anxiolytics. Syndrome manifests with diverse, often painful physical and psychological symptoms, which include but not limited to intense drug craving, anxiety, depression, insomnia, nausea, perspiration, body aches, tremors, hallucinations, and convulsions. [from NCI]

MedGen UID:
20990
Concept ID:
C0038587
Mental or Behavioral Dysfunction
19.

Mental disorder

A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [from NCI]

MedGen UID:
14047
Concept ID:
C0004936
Mental or Behavioral Dysfunction
20.

Marijuana-Related Disorder

MedGen UID:
1391701
Concept ID:
C4505254
Mental or Behavioral Dysfunction
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