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Items: 4

1.

Premature birth

The birth of a baby of less than 37 weeks of gestational age. [from HPO]

MedGen UID:
535197
Concept ID:
C0233315
Finding
2.

17 alpha-hydroxyprogesterone

A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES. [from MeSH]

MedGen UID:
23467
Concept ID:
C0045010
Hormone; Organic Chemical; Pharmacologic Substance
3.

Hydroxyprogesterone

Metabolites or derivatives of PROGESTERONE with hydroxyl group substitution at various sites. [from MeSH]

MedGen UID:
9351
Concept ID:
C0020387
Hormone; Organic Chemical; Pharmacologic Substance
4.

Hydroxyprogesterone caproate

A synthetic progestational agent similar to the endogenous progesterone used in hormone therapy or as a female contraceptive. Mimicking the action of progesterone, hydroxyprogesterone caporate binds to and activates nuclear progesterone receptors in the reproductive system and causes the ligand-receptor complex to be translocated to the nucleus where it binds to and promotes expression of target genes. Due to the negative feedback mechanism seen with progesterone, this agent also blocks luteinizing hormone (LH) release from the pituitary gland, thereby leading to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. Furthermore, without stimulation of LH, estrogen release from the ovaries is stopped, hence impeding the growth of estrogen-sensitive tumor cells. [from NCI]

MedGen UID:
53386
Concept ID:
C0044971
Hormone; Organic Chemical; Pharmacologic Substance
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