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Items: 3

1.

Zaleplon

A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid (GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding. [from NCI]

MedGen UID:
117853
Concept ID:
C0251504
Organic Chemical; Pharmacologic Substance
2.

Insomnia

MedGen UID:
409589
Concept ID:
C1963237
Finding
3.

Insomnia

A sleep disorder characterized by difficulty in falling asleep and/or remaining asleep. [from NCI]

MedGen UID:
214589
Concept ID:
C0917801
Sign or Symptom
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