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Items: 1 to 20 of 26

1.

Methylation

The covalent chemical or biochemical addition of a methyl group(s) to a compound. (NCI) [from NCI]

MedGen UID:
44400
Concept ID:
C0025723
Molecular Function
2.

Absence

MedGen UID:
739164
Concept ID:
C1689985
Anatomical Abnormality
3.

Maternal

Having to do with the mother, coming from the mother, or related through the mother. [from NCI_NCI-GLOSS]

MedGen UID:
348949
Concept ID:
C1858460
Finding
4.

Abnormality

A condition that differs from the usual physical or mental state. [from NCI]

MedGen UID:
309940
Concept ID:
C1704258
Finding
5.

Tumorigenesis

A pathologic process that involves the transformation of normal cells to a neoplastic state and resulting in polyclonal or monoclonal neoplastic cell proliferation. [from NCI]

MedGen UID:
3302
Concept ID:
C0007621
Neoplastic Process
6.

Vidaza

MedGen UID:
288801
Concept ID:
C1563756
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
7.

Intracranial Neoplasm

A tumor that occurs in the brain. [from NCI_NCI-GLOSS]

MedGen UID:
287152
Concept ID:
C1527390
Neoplastic Process
8.

NSC-102816

MedGen UID:
209173
Concept ID:
C0878254
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
9.

Allelic Imbalance

A situation where one member (allele) of a gene pair is lost (LOSS OF HETEROZYGOSITY) or amplified. [from MeSH]

MedGen UID:
168420
Concept ID:
C0887935
Cell or Molecular Dysfunction
10.

Malignant Supratentorial Neoplasm

MedGen UID:
155589
Concept ID:
C0751589
Neoplastic Process
11.

DNA Methylation

The process by which methyl groups are added to nucleotides in genomic DNA. [from NCI]

MedGen UID:
138191
Concept ID:
C0376452
Molecular Function
12.

Neoplasm of the central nervous system

A neoplasm of the central nervous system. [from HPO]

MedGen UID:
88335
Concept ID:
C0085136
Neoplastic Process
13.

Abnormality of the pituitary gland

Your pituitary gland is a pea-sized gland at the base of your brain. The pituitary is the "master control gland" - it makes hormones that affect growth and the functions of other glands in the body. . With pituitary disorders, you often have too much or too little of one of your hormones. Injuries can cause pituitary disorders, but the most common cause is a pituitary tumor.  [from MedlinePlus]

MedGen UID:
45934
Concept ID:
C0032002
Disease or Syndrome
14.

Neoplasm of the nervous system

A tumor (abnormal growth of tissue) of the nervous system. [from HPO]

MedGen UID:
45046
Concept ID:
C0027766
Neoplastic Process
15.

Unspecified encephalopathy

Encephalopathy is a term that means brain disease, damage, or malfunction. In general, encephalopathy is manifested by an altered mental state. [from HPO]

MedGen UID:
39314
Concept ID:
C0085584
Disease or Syndrome
16.

Neoplasm of the pituitary gland

Your pituitary gland is a pea-sized gland at the base of your brain. The pituitary is the master control gland - it makes hormones that affect growth and the functions of other glands in the body. . Pituitary tumors are common, but often they don't cause health problems. Most people with pituitary tumors never even know they have them. The most common type of pituitary tumor produces hormones and disrupts the balance of hormones in your body. This can cause endocrine diseases such as Cushing's syndrome and hyperthyroidism. Symptoms of pituitary tumors include. -Headaches . -Vision problems. -Nausea and vomiting. -Problems caused by the production of too many hormones. Pituitary tumors are usually curable. Treatment is often surgery to remove the tumor. Other options include medicines, radiation therapy, and chemotherapy.  [from MedlinePlus]

MedGen UID:
19326
Concept ID:
C0032019
Neoplastic Process
17.

Neoplasm of brain

A brain tumor is a growth of abnormal cells in the tissues of the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Some are primary brain tumors, which start in the brain. Others are metastatic, and they start somewhere else in the body and move to the brain. Brain tumors can cause many symptoms. Some of the most common are. -Headaches, often in the morning . -Nausea and vomiting. -Changes in your ability to talk, hear, or see. -Problems with balance or walking. -Problems with thinking or memory . -Feeling weak or sleepy. -Changes in your mood or behavior. -Seizures. Doctors diagnose brain tumors by doing a neurologic exam and tests including an MRI, CT scan, and biopsy. Treatment options include watchful waiting, surgery, radiation therapy, chemotherapy, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. Many people get a combination of treatments. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
14216
Concept ID:
C0006118
Neoplastic Process
18.

Disorder of brain

The brain is the control center of the body. It controls thoughts, memory, speech, and movement. It regulates the function of many organs. When the brain is healthy, it works quickly and automatically. However, when problems occur, the results can be devastating. . Inflammation in the brain can lead to problems such as vision loss, weakness and paralysis. Loss of brain cells, which happens if you suffer a stroke, can affect your ability to think clearly. Brain tumors can also press on nerves and affect brain function. Some brain diseases are genetic. And we do not know what causes some brain diseases, such as Alzheimer's disease. The symptoms of brain diseases vary widely depending on the specific problem. In some cases, damage is permanent. In other cases, treatments such as surgery, medicines, or physical therapy can correct the source of the problem or improve symptoms. .  [from MedlinePlus]

MedGen UID:
14214
Concept ID:
C0006111
Disease or Syndrome
19.

Supratentorial neoplasm

Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and BRAIN STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation. [from MeSH]

MedGen UID:
11663
Concept ID:
C0038874
Neoplastic Process
20.

Disorder of hypothalamus

Neoplastic, inflammatory, infectious, and other diseases of the hypothalamus. Clinical manifestations include appetite disorders; AUTONOMIC NERVOUS SYSTEM DISEASES; SLEEP DISORDERS; behavioral symptoms related to dysfunction of the LIMBIC SYSTEM; and neuroendocrine disorders. [from MeSH]

MedGen UID:
6988
Concept ID:
C0020655
Disease or Syndrome
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