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Items: 9

1.

Intracranial Neoplasm

A benign or malignant neoplasm that arises from or metastasizes to structures within the cranium. This includes meningeal and other tumors that occur in the spaces that surround the brain, and neoplasms of the brain. [from NCI]

MedGen UID:
287152
Concept ID:
C1527390
Neoplastic Process
2.

Neurocutaneous melanosis

Neurocutaneous melanosis, or neuromelanosis, is characterized by the presence of melanin-producing cells within the brain parenchyma or leptomeninges, which may lead to clinically apparent neurologic signs and symptoms, such as seizures. Other neurologic abnormalities, including hydrocephalus, arachnoid cysts, tumors, and syringomyelia, may also occur. The disorder is a rare but severe manifestation of congenital melanocytic nevus syndrome (CMNS; 137550). Some patients with neurocutaneous melanosis or CMNS may develop malignant melanoma. The incidence of neurologic involvement, development of malignant melanoma, and death is significantly associated with the projected adult size of the largest congenital melanocytic nevus, particularly those greater than 40 cm (summary by Kinsler et al., 2008; Kinsler et al., 2013). [from GTR]

MedGen UID:
154259
Concept ID:
C0544862
Pathologic Function
3.

Nevus

A circumscribed stable malformation of the skin and occasionally of the oral mucosa, which is not due to external causes and therefore presumed to be of hereditary origin. [from MeSH]

MedGen UID:
45074
Concept ID:
C0027960
Neoplastic Process
4.

Melanosis

Disorders of increased melanin pigmentation that develop without preceding inflammatory disease. [from MeSH]

MedGen UID:
44344
Concept ID:
C0025209
Disease or Syndrome
5.

Blue nevus

MedGen UID:
452034
Concept ID:
CN117704
Finding
6.

Blue Nevus

An intradermal nevus characterized by the presence of benign pigmented dendritic spindle-shaped melanocytes. It most frequently occurs in the skin of the distal upper extremities, followed by the lower extremities, scalp, face, and buttocks. It usually presents as a single blue or blue-black papular lesion less than 1cm in diameter. Simple excision is usually curative. [from NCI]

MedGen UID:
104930
Concept ID:
C0206736
Neoplastic Process
7.

Mongolian blue spot

A bluish-gray to gray-brown benign, melanocytic nevus found usually in the LUMBOSACRAL REGION of dark-skinned people, especially those of East Asian ancestry. It is usually congenital or appears shortly after birth, and disappears in childhood. [from MeSH]

MedGen UID:
75591
Concept ID:
C0265985
Neoplastic Process
8.

Pigmented tumor

MedGen UID:
722536
Concept ID:
C1300817
Finding
9.

Cellular Blue Nevus

A blue nevus characterized by a multinodular cellular infiltrate with a dumb-bell architecture occupying the reticular dermis. The cellular infiltrate often extends into the subcutaneous tissue. The cellular infiltrate is composed of spindle-shaped melanocytes with pale cytoplasm alternating with bundles of pigmented spindle-shaped melanocytes. In occasional cases an increased mitotic activity, focal necrosis, and nuclear pleomorphism may be seen. Such cases with atypical features may have an uncertain malignant potential. [from NCI]

MedGen UID:
137764
Concept ID:
C0334448
Neoplastic Process
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