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Ellagic Acid

MedGen UID:
4912
Concept ID:
C0013900
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
Synonyms: (1)Benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione, 2,3,7,8-tetrahydroxy-; Acid, Benzoaric; Acid, Ellagic; Benzoaric Acid
 

Definition

A fused four ring compound occurring free or combined in galls. Isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used in research and as a dye. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEllagic Acid

Recent clinical studies

Etiology

Guo H, Zhang D, Fu Q
Med Sci Monit 2016 Dec 12;22:4881-4886. PMID: 27941714Free PMC Article
Wang D, Chen Q, Liu B, Li Y, Tan Y, Yang B
Acta Cir Bras 2016 Feb;31(2):143-9. doi: 10.1590/S0102-865020160020000010. PMID: 26959625
Ortiz-Ruiz CV, Berna J, Tudela J, Varon R, Garcia-Canovas F
J Dermatol Sci 2016 May;82(2):115-22. Epub 2016 Feb 12 doi: 10.1016/j.jdermsci.2016.02.004. PMID: 26899308
Sayar I, Bicer S, Gursul C, Gürbüzel M, Peker K, Işik A
J Obstet Gynaecol Res 2016 Jan;42(1):52-8. Epub 2015 Nov 10 doi: 10.1111/jog.12858. PMID: 26555146
Mishra S, Vinayak M
BMC Complement Altern Med 2015 Aug 15;15:281. doi: 10.1186/s12906-015-0810-5. PMID: 26276710Free PMC Article

Diagnosis

Liang WZ, Chou CT, Cheng JS, Wang JL, Chang HT, Chen IS, Lu T, Yeh JH, Kuo DH, Shieh P, Chen FA, Kuo CC, Jan CR
Eur J Pharmacol 2016 Jun 5;780:243-51. Epub 2016 Mar 30 doi: 10.1016/j.ejphar.2016.03.057. PMID: 27038520
Alfredsson CF, Rendel F, Liang QL, Sundström BE, Nånberg E
Biomed Pharmacother 2015 Dec;76:39-45. Epub 2015 Nov 10 doi: 10.1016/j.biopha.2015.10.008. PMID: 26653548
Alfredsson CF, Ding M, Liang QL, Sundström BE, Nånberg E
Biomed Pharmacother 2014 Feb;68(1):129-35. Epub 2013 Aug 30 doi: 10.1016/j.biopha.2013.08.010. PMID: 24051122
Weisburg JH, Schuck AG, Reiss SE, Wolf BJ, Fertel SR, Zuckerbraun HL, Babich H
Anticancer Res 2013 May;33(5):1829-36. PMID: 23645727
Kumano O, Ieko M, Naito S, Yoshida M, Takahashi N
J Thromb Haemost 2012 Nov;10(11):2338-43. doi: 10.1111/j.1538-7836.2012.04906.x. PMID: 22909048

Therapy

Derosa G, Maffioli P, Sahebkar A
Adv Exp Med Biol 2016;928:473-479. doi: 10.1007/978-3-319-41334-1_20. PMID: 27671829
Ahmed T, Setzer WN, Nabavi SF, Orhan IE, Braidy N, Sobarzo-Sanchez E, Nabavi SM
Curr Pharm Des 2016;22(10):1350-60. PMID: 26806345
Mishra S, Vinayak M
BMC Complement Altern Med 2015 Aug 15;15:281. doi: 10.1186/s12906-015-0810-5. PMID: 26276710Free PMC Article
Park SW, Kwon MJ, Yoo JY, Choi HJ, Ahn YJ
BMC Complement Altern Med 2014 May 26;14:171. doi: 10.1186/1472-6882-14-171. PMID: 24885569Free PMC Article
Alfredsson CF, Ding M, Liang QL, Sundström BE, Nånberg E
Biomed Pharmacother 2014 Feb;68(1):129-35. Epub 2013 Aug 30 doi: 10.1016/j.biopha.2013.08.010. PMID: 24051122

Prognosis

Zhao J, Li G, Bo W, Zhou Y, Dang S, Wei J, Li X, Liu M
Int J Oncol 2017 Feb;50(2):613-621. Epub 2017 Jan 5 doi: 10.3892/ijo.2017.3843. PMID: 28101576
Chang TL, Lin SW, Wu SL, Hong CM
J Nutr Biochem 2013 Nov;24(11):1970-81. Epub 2013 Sep 26 doi: 10.1016/j.jnutbio.2013.07.001. PMID: 24075904
García-Villalba R, Beltrán D, Espín JC, Selma MV, Tomás-Barberán FA
J Agric Food Chem 2013 Sep 18;61(37):8797-806. Epub 2013 Sep 6 doi: 10.1021/jf402498b. PMID: 23984796
Vanella L, Barbagallo I, Acquaviva R, Di Giacomo C, Cardile V, Abraham NG, Sorrenti V
Curr Pharm Des 2013;19(15):2728-36. PMID: 23092326
Berni A, Grossi MR, Pepe G, Filippi S, Muthukumar S, Papeschi C, Natarajan AT, Palitti F
Mutat Res 2012 Jul 4;746(1):60-5. Epub 2012 Mar 27 doi: 10.1016/j.mrgentox.2012.03.007. PMID: 22475933

Clinical prediction guides

Dubey A, Park DW, Kwon JE, Jeong YJ, Kim T, Kim I, Kang SC, Chi KW
Int J Nanomedicine 2015;10 Spec Iss:227-40. Epub 2015 Sep 2 doi: 10.2147/IJN.S88289. PMID: 26366074Free PMC Article
Ramírez de Molina A, Vargas T, Molina S, Sánchez J, Martínez-Romero J, González-Vallinas M, Martín-Hernández R, Sánchez-Martínez R, Gómez de Cedrón M, Dávalos A, Calani L, Del Rio D, González-Sarrías A, Espín JC, Tomás-Barberán FA, Reglero G
J Pharmacol Exp Ther 2015 May;353(2):433-44. Epub 2015 Mar 10 doi: 10.1124/jpet.114.221796. PMID: 25758919
Naiki-Ito A, Chewonarin T, Tang M, Pitchakarn P, Kuno T, Ogawa K, Asamoto M, Shirai T, Takahashi S
Prostate 2015 Feb;75(2):151-60. Epub 2014 Oct 4 doi: 10.1002/pros.22900. PMID: 25284475
Ho CC, Huang AC, Yu CS, Lien JC, Wu SH, Huang YP, Huang HY, Kuo JH, Liao WY, Yang JS, Chen PY, Chung JG
Environ Toxicol 2014 Nov;29(11):1262-74. Epub 2013 Mar 30 doi: 10.1002/tox.21857. PMID: 23554011
Munagala R, Aqil F, Vadhanam MV, Gupta RC
Cancer Lett 2013 Oct 10;339(2):175-84. Epub 2013 Jun 18 doi: 10.1016/j.canlet.2013.06.012. PMID: 23791885Free PMC Article

Recent systematic reviews

Acharya N, Acharya S, Shah U, Shah R, Hingorani L
J Ethnopharmacol 2016 Apr 2;181:236-51. Epub 2016 Feb 3 doi: 10.1016/j.jep.2016.01.043. PMID: 26851499
Burton-Freeman BM, Sandhu AK, Edirisinghe I
Adv Nutr 2016 Jan;7(1):44-65. Epub 2016 Jan 15 doi: 10.3945/an.115.009639. PMID: 26773014Free PMC Article
Alasalvar C, Bolling BW
Br J Nutr 2015 Apr;113 Suppl 2:S68-78. doi: 10.1017/S0007114514003729. PMID: 26148924
Kapoor D, Vijayvergiya R, Dhawan V
J Ethnopharmacol 2014 Sep 11;155(2):1029-45. Epub 2014 Jul 8 doi: 10.1016/j.jep.2014.06.056. PMID: 25014508
Banihani S, Swedan S, Alguraan Z
Nutr Res 2013 May;33(5):341-8. Epub 2013 Apr 15 doi: 10.1016/j.nutres.2013.03.003. PMID: 23684435

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