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Items: 18

1.

Dementia

Dementia is the name for a group of symptoms caused by disorders that affect the brain. It is not a specific disease. People with dementia may not be able to think well enough to do normal activities, such as getting dressed or eating. They may lose their ability to solve problems or control their emotions. Their personalities may change. They may become agitated or see things that are not there. . Memory loss is a common symptom of dementia. However, memory loss by itself does not mean you have dementia. People with dementia have serious problems with two or more brain functions, such as memory and language. Although dementia is common in very elderly people, it is not part of normal aging. Many different diseases can cause dementia, including Alzheimer's disease and stroke. Drugs are available to treat some of these diseases. While these drugs cannot cure dementia or repair brain damage, they may improve symptoms or slow down the disease. NIH: National Institute of Neurological Disorders and Stroke.  [from MedlinePlus]

MedGen UID:
99229
Concept ID:
C0497327
Finding; Mental or Behavioral Dysfunction
2.

Frontotemporal dementia

The clinical manifestations of MAPT-related disorders (MAPT-related tauopathies) are most typically those of frontotemporal dementia (FTDP-17), but also include progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), mild late-onset parkinsonism, and dementia with epilepsy. Clinical presentation of frontotemporal dementia (FTD) is variable: some present with slowly progressive behavioral changes, language disturbances, and/or extrapyramidal signs, whereas others present with rigidity, bradykinesia, supranuclear palsy, and saccadic eye movement disorders. Onset is usually between ages 40 and 60 years, but may be earlier or later. The disease progresses over a few years into profound dementia with mutism. PSP is characterized by progressive vertical gaze palsy in combination with a prominent loss of balance at early stages of the disease. With progression, axial rigidity, dysarthria, and dysphagia become prominent, often in combination with a frontal dysexecutive syndrome. CBD is a progressive neurodegenerative disorder which affects both the frontoparietal cortex and the basal ganglia, resulting in a mild to moderate dementia in combination with asymmetric parkinsonism, ideomotor apraxia, aphasia, and an alien-hand syndrome. [from GeneReviews]

MedGen UID:
83266
Concept ID:
C0338451
Disease or Syndrome
3.

Trazodone

A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309) [from MeSH]

MedGen UID:
21633
Concept ID:
C0040805
Organic Chemical; Pharmacologic Substance
4.

Frontotemporal dementia

A dementia associated with degeneration of the frontotemporal lobe and clinically associated with personality and behavioral changes such as disinhibition, apathy, and lack of insight. The hallmark feature of frontotemporal dementia is the presentation with focal syndromes such as progressive language dysfunction, or aphasia, or behavioral changes characteristic of frontal lobe disorders. [from HPO]

MedGen UID:
505124
Concept ID:
CN001944
Finding
5.

Thombran

MedGen UID:
327767
Concept ID:
C1564456
Organic Chemical; Pharmacologic Substance
6.

Trazon

MedGen UID:
296063
Concept ID:
C1564459
Organic Chemical; Pharmacologic Substance
7.

Deprax

MedGen UID:
296062
Concept ID:
C1564450
Organic Chemical; Pharmacologic Substance
8.

ratio-Trazodone

MedGen UID:
289830
Concept ID:
C1564455
Organic Chemical; Pharmacologic Substance
9.

PMS-Trazodone

MedGen UID:
289829
Concept ID:
C1564454
Organic Chemical; Pharmacologic Substance
10.

Apo-Trazodone

MedGen UID:
289828
Concept ID:
C1564449
Organic Chemical; Pharmacologic Substance
11.

Trazodon-neuraxpharm

MedGen UID:
288971
Concept ID:
C1564458
Organic Chemical; Pharmacologic Substance
12.

Nu-Trazodone

MedGen UID:
288969
Concept ID:
C1564453
Organic Chemical; Pharmacologic Substance
13.

Novo-Trazodone

MedGen UID:
288968
Concept ID:
C1564452
Organic Chemical; Pharmacologic Substance
14.

Gen-Trazodone

MedGen UID:
288967
Concept ID:
C1564451
Organic Chemical; Pharmacologic Substance
15.

Molipaxin

MedGen UID:
182441
Concept ID:
C0917896
Organic Chemical; Pharmacologic Substance
16.

AF-1161

MedGen UID:
182440
Concept ID:
C0917895
Organic Chemical; Pharmacologic Substance
17.

Desyrel

MedGen UID:
147289
Concept ID:
C0701914
Organic Chemical; Pharmacologic Substance
18.

Trittico

MedGen UID:
160
Concept ID:
C0001717
Organic Chemical; Pharmacologic Substance
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