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Items: 1 to 20 of 44

1.

Alpha Heavy Chain Disease

A clonal disorder, also known as immunoproliferative small intestinal disease or Mediterranean lymphoma, characterised by the secretion of a defective alpha heavy chain. It predominantly affects young people in the Mediterranean region. It involves the small intestine, and patients usually present with malabsorption syndrome, abdominal pain, weight loss, and fever. There is extensive villous atrophy of the small intestinal mucosa, which is heavily infiltrated by small lymphocytes and plasma cells. The small intestinal morphologic changes are consistent with a mucosa-associated lymphoid tissue lymphoma (MALT lymphoma). [from NCI]

MedGen UID:
7039
Concept ID:
C0021071
Neoplastic Process
2.

Alpha-heavy chain disease

Alpha-heavy chain disease (alpha-HCD) is a type of HCD (see this term) characterized by the production of incomplete monoclonal alpha-heavy chains without associated light chains. Alpha-HCD is considered to be a subtype of immunoproliferative small intestinal disease (IPSID; see this term). The clinical presentation includes chronic diarrhea with evidence of malabsorption. [from ORDO]

MedGen UID:
830913
Concept ID:
CN197330
Disease or Syndrome
3.

Lymphoma

A cancer originating in lymphocytes and presenting as a solid tumor of lymhpoid cells. [from HPO]

MedGen UID:
44223
Concept ID:
C0024299
Neoplastic Process
4.

Causative_agents

Definition: A factor, such as a microorganism, chemical substance, or form of radiation, whose presence, excessive presence, or (in deficiency diseases) relative absence is essential, in whole or in part, for the occurrence of a condition. Constraint: The use of this participation is limited to observations.  [from HL7]

MedGen UID:
623004
Concept ID:
C0449411
Finding
5.

Lymphoma

A cancer originating in lymphocytes and presenting as a solid tumor of lymhpoid cells. [from HPO]

MedGen UID:
505322
Concept ID:
CN002422
Finding
6.

Sulfoxide

the chemical group =SO. [from CRISP]

MedGen UID:
678482
Concept ID:
C0851343
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
7.

2-Pyridinylmethylsulfinylbenzimidazoles

Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS. [from MeSH]

MedGen UID:
314121
Concept ID:
C1721069
Organic Chemical; Pharmacologic Substance
8.

Monoclonal Gammopathy

An abnormal laboratory test result indicating the presence of monoclonal immunoglobulins in the blood or urine. [from NCI]

MedGen UID:
210153
Concept ID:
C1136085
Neoplastic Process
9.

Antimicrobial substance

Generically, any agent that destroys microbes. However, usage of the term is increasingly being confined to agents that prevent or reduce the transmission of SEXUALLY TRANSMITTED DISEASES. [from MeSH]

MedGen UID:
209727
Concept ID:
C1136254
Pharmacologic Substance
10.

Prilosec

MedGen UID:
148645
Concept ID:
C0700777
Organic Chemical; Pharmacologic Substance
11.

Lymphatism

MedGen UID:
141817
Concept ID:
C0524631
Disease or Syndrome
12.

Disease due to Gram-negative bacteria

Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method. [from MeSH]

MedGen UID:
88406
Concept ID:
C0085423
Disease or Syndrome
13.

Intestinal Neoplasm

A benign or malignant neoplasm involving the small or large intestine. [from NCI]

MedGen UID:
43932
Concept ID:
C0021841
Neoplastic Process
14.

Immunoglobulin A

Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions. [from MeSH]

MedGen UID:
43820
Concept ID:
C0020835
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
15.

Omeprazole

A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. [from MeSH]

MedGen UID:
18166
Concept ID:
C0028978
Organic Chemical; Pharmacologic Substance
16.

Campylobacteriosis

Infections with bacteria of the genus CAMPYLOBACTER. [from MeSH]

MedGen UID:
14296
Concept ID:
C0006818
Disease or Syndrome
17.

Bacterial infection by site

An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections. [from NCI]

MedGen UID:
14012
Concept ID:
C0004623
Disease or Syndrome
18.

Paraproteinemia

A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin. [from MeSH]

MedGen UID:
10577
Concept ID:
C0030489
Disease or Syndrome
19.

Abnormality of the lymphatic system

An anomaly of the lymphatic system, a network of lymphatic vessels that carry a clear fluid called lymph unidirectionally towards either the right lymphatic duct or the thoracic duct, which in turn drain into the right and left subclavian veins respectively. [from HPO]

MedGen UID:
9829
Concept ID:
C0024228
Disease or Syndrome
20.

Gastrointestinal disease

A non-neoplastic or neoplastic disorder that affects the gastrointestinal tract, anus, liver, biliary system, and pancreas. [from NCI]

MedGen UID:
8970
Concept ID:
C0017178
Disease or Syndrome
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