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Items: 11

1.

Ramipril

A long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat. [from MeSH]

MedGen UID:
35138
Concept ID:
C0072973
Organic Chemical; Pharmacologic Substance
2.

Drug-Induced Liver Injury, Chronic

Liver disease lasting six months or more, caused by an adverse drug effect. The adverse effect may result from a direct toxic effect of a drug or metabolite, or an idiosyncratic response to a drug or metabolite. [from MeSH]

MedGen UID:
403442
Concept ID:
C2717837
Disease or Syndrome
3.

Fozitec

MedGen UID:
292624
Concept ID:
C1567475
Organic Chemical; Pharmacologic Substance
4.

Hiperlex

MedGen UID:
291354
Concept ID:
C1567479
Amino Acid, Peptide, or Protein; Pharmacologic Substance
5.

Dynacil

MedGen UID:
291352
Concept ID:
C1567477
Organic Chemical; Pharmacologic Substance
6.

Fosinil

MedGen UID:
291351
Concept ID:
C1567476
Organic Chemical; Pharmacologic Substance
7.

Newace

MedGen UID:
147524
Concept ID:
C0728957
Amino Acid, Peptide, or Protein; Pharmacologic Substance
8.

SQ-28,555

MedGen UID:
107769
Concept ID:
C0543474
Amino Acid, Peptide, or Protein; Pharmacologic Substance
9.

Drug-induced chronic hepatitis

MedGen UID:
105625
Concept ID:
C0524912
Disease or Syndrome
10.

Fosinopril

A phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As an ester prodrug, fosinopril is hydrolysed by esterases to its active metabolite fosinoprilat. Fosinoprilat specifically and competitively inhibits angiotensin-converting enzyme thereby decreasing the formation of the potent vasoconstrictor angiotensin II, resulting in diminished vasopressor activity. In addition, angiotensin II-mediated aldosterone secretion by adrenal cortex is decreased, which results in a decrease of sodium retention and an increase in water outflow. [from NCI]

MedGen UID:
49641
Concept ID:
C0118168
Organic Chemical; Pharmacologic Substance
11.

Extravasation of bile

MedGen UID:
568983
Concept ID:
C0333253
Pathologic Function
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