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Items: 7

1.

Arterial blood pressure

The blood pressure in the ARTERIES. It is commonly measured with a SPHYGMOMANOMETER on the upper arm which represents the arterial pressure in the BRACHIAL ARTERY. [from MeSH]

MedGen UID:
473370
Concept ID:
C1272641
Finding
2.

AGON

Used with chemicals, drugs, and endogenous substances to indicate substances or agents that have affinity for a receptor and intrinsic activity at that receptor. (From Textbook of Pharmacology, 1991, p.16) [from MeSH]

MedGen UID:
116746
Concept ID:
C0243192
Pharmacologic Substance
3.

Adenosine A3 Receptor Agonists

Drugs that selectively bind to and activate ADENOSINE A3 RECEPTORS. [from MeSH]

MedGen UID:
422383
Concept ID:
C2936553
Pharmacologic Substance
4.

tri-1',5',5'-N,N,N-mono-8'-O-methylstreptonigrone

MedGen UID:
136383
Concept ID:
C0650924
Organic Chemical; Pharmacologic Substance
5.

antidepressants response - Efficacy

MedGen UID:
881079
Concept ID:
CN236478
Sign or Symptom
6.

Selective serotonin reuptake inhibitors response - Efficacy

MedGen UID:
880938
Concept ID:
CN236561
Sign or Symptom
7.

Sertraline response

Selective serotonin reuptake inhibitors (SSRIs) are used for the treatment of major depressive and anxiety disorders, and may be used to treat other psychiatric conditions. Sertraline is in part metabolized by cytochrome P450 2C19 (CYP2C19) and variations in CYP2C19 may affect drug exposure. CYP2C19 poor metabolizers might exhibit reduced oral clearance of sertraline and side effects in CYP2C19 poor metabolizers have also been reported to be more frequent than in normal metabolizers. Therapeutic guidelines for the SSRI sertraline based on CYP2C19 genotype have been published in Clinical Pharmacology and Therapeutics by the Clinical Pharmacogenetics Implementation Consortium (CPIC) and are available on the PharmGKB website. [from GTR]

MedGen UID:
808067
Concept ID:
CN221265
Sign or Symptom
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