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Items: 1 to 20 of 39

1.

Lymphoma

MedGen UID:
44223
Concept ID:
C0024299
Neoplastic Process
2.

Lymphoma

MedGen UID:
505322
Concept ID:
CN002422
Finding
3.

Hepatosplenic T-Cell Lymphoma

An extranodal, mature T-cell non-Hodgkin lymphoma that originates from cytotoxic T-cells, usually of gamma/delta T-cell type. It is characterized by the presence of medium-size neoplastic lymphocytes infiltrating the hepatic sinusoids. A similar infiltrating pattern is also present in the spleen and bone marrow that are usually involved at the time of the diagnosis. [from NCI]

MedGen UID:
272711
Concept ID:
C1333984
Neoplastic Process
4.

T-cell lymphoma

MedGen UID:
86957
Concept ID:
C0079772
Neoplastic Process
5.

Diffuse Mixed Cell Lymphoma

An antiquated term referring to non-Hodgkin lymphomas with a mixed cellular composition. This term applies to both B- and T- cell non-Hodgkin lymphomas. [from NCI]

MedGen UID:
42542
Concept ID:
C0079757
Neoplastic Process
6.

Fibrosis

MedGen UID:
5179
Concept ID:
C0016059
Pathologic Function
7.

Absence

MedGen UID:
739164
Concept ID:
C1689985
Anatomical Abnormality
8.

Sinusoidal Infiltration

A microscopic finding indicating the invasion of sinusoidal spaces by malignant cells. [from NCI]

MedGen UID:
275434
Concept ID:
C1519333
Finding
9.

Aggressive Clinical Course

MedGen UID:
233968
Concept ID:
C1332223
Finding
10.

Transient ischemic attack

MedGen UID:
181489
Concept ID:
C0917805
Disease or Syndrome
11.

Severe

Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
104640
Concept ID:
C0205082
Qualitative Concept
12.

Infiltration

The process of the diffusion or accumulation in a tissue or cells of a substance not normal to it or in amounts above normal. (NCI) [from NCI]

MedGen UID:
83059
Concept ID:
C0332448
Pathologic Function
13.

Jaundice

MedGen UID:
43987
Concept ID:
C0022346
Sign or Symptom
14.

Retinitis pigmentosa

Retinitis pigmentosa (RP) refers to a heterogeneous group of inherited ocular diseases that result in a progressive retinal degeneration affecting 1 in 3,000 to 5,000 people (Veltel et al., 2008). Symptoms include night blindness, the development of tunnel vision, and slowly progressive decreased central vision starting at approximately 20 years of age. Upon examination, patients have decreased visual acuity, constricted visual fields, dyschromatopsia (tritanopic; see 190900), and the classic fundus appearance with dark pigmentary clumps in the midperiphery and perivenous areas ('bone spicules'), attenuated retinal vessels, cystoid macular edema, fine pigmented vitreous cells, and waxy optic disc pallor. RP is associated with posterior subcapsular cataracts in 39 to 72% of patients, high myopia, astigmatism, keratoconus, and mild hearing loss in 30% of patients (excluding patients with Usher syndrome; see 276900). Fifty percent of female carriers of X-linked RP have a golden reflex in the posterior pole (summary by Kaiser et al., 2004). Juvenile Retinitis Pigmentosa Autosomal recessive childhood-onset severe retinal dystrophy is a heterogeneous group of disorders affecting rod and cone photoreceptors simultaneously. The most severe cases are termed Leber congenital amaurosis (see 204000), whereas the less aggressive forms are usually considered juvenile retinitis pigmentosa (Gu et al., 1997). Autosomal recessive forms of juvenile retinitis pigmentosa can be caused by mutation in the SPATA7 (609868), LRAT (604863), and TULP1 (602280) genes (see LCA3, 604232, LCA14, 613341, and LCA15, 613843, respectively). An autosomal dominant form of juvenile retinitis pigmentosa (see 604393) is caused by mutation in the AIPL1 gene (604392). [from OMIM]

MedGen UID:
20551
Concept ID:
C0035334
Disease or Syndrome
15.

Hepatosplenomegaly

MedGen UID:
9225
Concept ID:
C0019214
Sign or Symptom
16.

Lymphosarcoma

An antiquated term that refers to a non-Hodgkin lymphoma composed of small and medium sized lymphocytes. [from NCI]

MedGen UID:
811370
Concept ID:
C3714542
Neoplastic Process
17.

Lymphatism

MedGen UID:
141817
Concept ID:
C0524631
Disease or Syndrome
18.

Protease preparation

A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule. [from NCI]

MedGen UID:
45389
Concept ID:
C0030946
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
19.

Diffuse non-Hodgkin lymphoma, undifferentiated

MedGen UID:
44226
Concept ID:
C0024306
Neoplastic Process
20.

Mixed Cell Lymphoma

An antiquated term that refers to a lymphoma composed of a mixture of small and large lymphocytes. [from NCI]

MedGen UID:
44225
Concept ID:
C0024304
Neoplastic Process
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