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1.

Colitis

Colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, cecum and rectum). Colitides may be acute and self-limited or chronic, and broadly fit into the category of digestive diseases. [from HPO]

MedGen UID:
40385
Concept ID:
C0009319
Disease or Syndrome
2.

Crohn disease

Crohn's disease causes inflammation of the digestive system. It is one of a group of diseases called inflammatory bowel disease. Crohn's can affect any area from the mouth to the anus. It often affects the lower part of the small intestine called the ileum. The cause of Crohn's disease is unknown. It may be due to an abnormal reaction by the body's immune system. It also seems to run in some families. It most commonly starts between the ages of 13 and 30. The most common symptoms are pain in the abdomen and diarrhea. Other symptoms include. -Bleeding from the rectum. -Weight loss. -Fever. Your doctor will diagnose Crohn's disease with a physical exam, lab tests, imaging tests, and a colonoscopy. Crohn's can cause complications, such as intestinal blockages, ulcers in the intestine, and problems getting enough nutrients. People with Crohn's can also have joint pain and skin problems. Children with the disease may have growth problems. There is no cure for Crohn's. Treatment can help control symptoms, and may include medicines, nutrition supplements, and/or surgery. Some people have long periods of remission, when they are free of symptoms. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.  [from MedlinePlus]

MedGen UID:
3664
Concept ID:
C0010346
Disease or Syndrome
3.

Crohn disease

MedGen UID:
909933
Concept ID:
CN043071
Disease or Syndrome
4.

Inflammation of the large intestine

MedGen UID:
662273
Concept ID:
C0578878
Disease or Syndrome; Pathologic Function
5.

Inflammation of the large intestine

MedGen UID:
505065
Concept ID:
CN001842
Finding
6.

Inflammatory bowel disease 5

MedGen UID:
342879
Concept ID:
C1853438
Disease or Syndrome
7.

Inflammatory bowel disease 1

MedGen UID:
146259
Concept ID:
C0678202
Disease or Syndrome
8.

Risk factor

Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury. [from NCI]

MedGen UID:
48477
Concept ID:
C0035648
Finding; Quantitative Concept
9.

Inflammatory bowel disease

A general term that refers to the inflammation of the colon and rectum. Inflammatory bowel disease includes ulcerative colitis and Crohn's disease. [from NCI_NCI-GLOSS]

MedGen UID:
43877
Concept ID:
C0021390
Disease or Syndrome
10.

Ulcer

The formation of a break on the skin or on the surface of an organ. An ulcer forms when the surface cells die and are cast off. Ulcers may be associated with cancer and other diseases. [from NCI]

MedGen UID:
22541
Concept ID:
C0041582
Disease or Syndrome; Pathologic Function
11.

Ulcerative colitis

Ulcerative colitis (UC) is a disease that causes inflammation and sores, called ulcers, in the lining of the rectum and colon. It is one of a group of diseases called inflammatory bowel disease. UC can happen at any age, but it usually starts between the ages of 15 and 30. It tends to run in families. The most common symptoms are pain in the abdomen and blood or pus in diarrhea. Other symptoms may include. -Anemia. -Severe tiredness. -Weight loss. -Loss of appetite. -Bleeding from the rectum. -Sores on the skin. -Joint pain. -Growth failure in children. About half of people with UC have mild symptoms. Doctors use blood tests, stool tests, colonoscopy or sigmoidoscopy, and imaging tests to diagnose UC. Several types of drugs can help control it. Some people have long periods of remission, when they are free of symptoms. In severe cases, doctors must remove the colon. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.  [from MedlinePlus]

MedGen UID:
3532
Concept ID:
C0009324
Disease or Syndrome
12.

Autoimmunity

The occurrence of an immune reaction against the organism's own cells or tissues. [from HPO]

MedGen UID:
505423
Concept ID:
CN002679
Finding
13.

Autoimmune reaction

A specific humoral or cell-mediated immune response against autologous (self) antigens. An autoimmune process may produce or be caused by autoimmune disease and may be developmentally complex, not necessarily pathological, and possibly pervasive. [from NCI]

MedGen UID:
105217
Concept ID:
C0443146
Pathologic Function
14.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
15.

disease transmission

Transmission of disease from one individual to another. [from PSY]

MedGen UID:
66979
Concept ID:
C0242781
Pathologic Function
16.

Autoimmune disease

Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. No one is sure what causes autoimmune diseases. They do tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases. There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting a diagnosis can be frustrating and stressful. Often, the first symptoms are fatigue, muscle aches and a low fever. The classic sign of an autoimmune disease is inflammation, which can cause redness, heat, pain and swelling. The diseases may also have flare-ups, when they get worse, and remissions, when symptoms get better or disappear. Treatment depends on the disease, but in most cases one important goal is to reduce inflammation. Sometimes doctors prescribe corticosteroids or other drugs that reduce your immune response.  [from MedlinePlus]

MedGen UID:
2135
Concept ID:
C0004364
Disease or Syndrome
17.

Hemorrhagic Rectocolitis

MedGen UID:
226206
Concept ID:
C1257847
Disease or Syndrome
18.

IIeocolitis

MedGen UID:
184943
Concept ID:
C0949272
Disease or Syndrome
19.

Genetic predisposition

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions. [from MeSH]

MedGen UID:
137259
Concept ID:
C0314657
Organism Attribute
20.

Crohn disease of ileum

MedGen UID:
82754
Concept ID:
C0267380
Disease or Syndrome
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