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Items: 4

1.

Smallpox vaccine

A live VACCINIA VIRUS vaccine of calf lymph or chick embryo origin, used for immunization against smallpox. It is now recommended only for laboratory workers exposed to smallpox virus. Certain countries continue to vaccinate those in the military service. Complications that result from smallpox vaccination include vaccinia, secondary bacterial infections, and encephalomyelitis. (Dorland, 28th ed) [from MeSH]

MedGen UID:
20786
Concept ID:
C0037355
Immunologic Factor; Pharmacologic Substance
2.

Hydranencephaly with renal aplasia-dysplasia

MARCH is an autosomal recessive lethal congenital disorder characterized by severe hydranencephaly with almost complete absence of the cerebral hemispheres, which are replaced by fluid, relative preservation of the posterior fossa structures, and renal dysplasia or agenesis. Affected fetuses either die in utero or shortly after birth, and show arthrogryposis and features consistent with anhydramnios. Histologic examination of residual brain tissue shows multinucleated neurons resulting from impaired cytokinesis (summary by Frosk et al., 2017). [from GTR]

MedGen UID:
343465
Concept ID:
C1856053
Disease or Syndrome
3.

Vaccine

Preparations containing substances with antigenic properties administered to activate the immune system, thereby inducing an immune response. [from NCI]

MedGen UID:
52963
Concept ID:
C0042210
Immunologic Factor; Pharmacologic Substance
4.

Smallpox

A condition that is caused by infection with Variola, and that is characterized by small, raised bumps. [from NCI]

MedGen UID:
20785
Concept ID:
C0037354
Disease or Syndrome
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