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Adhesion

MedGen UID:
7891
Concept ID:
C0001511
Acquired Abnormality; Pathologic Function
Synonyms: Adhesion, Tissue; Adhesions, Tissue; Tissue Adhesion; Tissue Adhesions
SNOMED CT: Adhesion (42685002)
 

Definition

Adhesions are bands of scar-like tissue. Normally, internal tissues and organs have slippery surfaces so they can shift easily as the body moves. Adhesions cause tissues and organs to stick together. They might connect the loops of the intestines to each other, to nearby organs, or to the wall of the abdomen. They can pull sections of the intestines out of place. This may block food from passing through the intestine. Adhesions can occur anywhere in the body. But they often form after surgery on the abdomen. Almost everyone who has surgery on the abdomen gets adhesions. Some adhesions don't cause any problems. But when they partly or completely block the intestines, they cause symptoms such as. -Severe abdominal pain or cramping. -Vomiting. -Bloating. -An inability to pass gas. -Constipation. Adhesions can sometimes cause infertility in women by preventing fertilized eggs from reaching the uterus. No tests are available to detect adhesions. Doctors usually find them during surgery to diagnose other problems. Some adhesions go away by themselves. If they partly block your intestines, a diet low in fiber can allow food to move easily through the affected area. If you have a complete intestinal obstruction, it is life threatening. You should get immediate medical attention and may need surgery. . NIH: National Institute of Diabetes and Digestive and Kidney Diseases.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdhesion

Recent clinical studies

Etiology

Ustyol A, Aycan Ustyol E, Gurdol F, Kokali F, Bekpınar S
Scand J Clin Lab Invest 2017 May;77(3):205-209. doi: 10.1080/00365513.2017.1292363. PMID: 28318371
Foy M, Anézo O, Saule S, Planque N
Exp Cell Res 2017 Apr 15;353(2):88-99. Epub 2017 Mar 8 doi: 10.1016/j.yexcr.2017.03.012. PMID: 28284838
Zhao C, Wang A, Lu F, Chen H, Fu P, Zhao X, Chen H
Tumour Biol 2017 Feb;39(2):1010428317691000. doi: 10.1177/1010428317691000. PMID: 28231727
He P, Liu D, Zhang B, Zhou G, Su X, Wang Y, Li D, Yang X
Cell Physiol Biochem 2017;41(2):689-700. Epub 2017 Feb 8 doi: 10.1159/000458428. PMID: 28214836
Mobasseri R, Tian L, Soleimani M, Ramakrishna S, Naderi-Manesh H
Biochem Biophys Res Commun 2017 Jan 29;483(1):312-317. Epub 2016 Dec 23 doi: 10.1016/j.bbrc.2016.12.146. PMID: 28025144

Diagnosis

Ustyol A, Aycan Ustyol E, Gurdol F, Kokali F, Bekpınar S
Scand J Clin Lab Invest 2017 May;77(3):205-209. doi: 10.1080/00365513.2017.1292363. PMID: 28318371
Zhao C, Wang A, Lu F, Chen H, Fu P, Zhao X, Chen H
Tumour Biol 2017 Feb;39(2):1010428317691000. doi: 10.1177/1010428317691000. PMID: 28231727
Tsoumani ME, Tatsidou PT, Ntalas IV, Goudevenos JA, Tselepis AD
Platelets 2016 Dec;27(8):812-820. Epub 2016 Jun 23 doi: 10.1080/09537104.2016.1192113. PMID: 27337147
Liu J, Wang Y, He S, Xu X, Huang Y, Tang J, Wu Y, Miao X, He Y, Wang Q, Liang L, Cheng C
Hematology 2016 Dec;21(10):603-612. Epub 2016 Jun 18 doi: 10.1080/10245332.2016.1147678. PMID: 27319807
White J, Krishnamoorthy S, Gupta D, Lancelot M, Moore N, Sarnaik S, Hobbs WE 2nd, Light DR, Hines P
Br J Haematol 2016 Sep;174(6):970-82. Epub 2016 Jun 12 doi: 10.1111/bjh.14158. PMID: 27291690

Therapy

Zhang D, Liu X, Gao J, Sun Y, Liu T, Yan Q, Yang X
Tumour Biol 2017 Mar;39(3):1010428317695973. doi: 10.1177/1010428317695973. PMID: 28349835
Diamond MP
Fertil Steril 2016 Oct;106(5):994-997.e1. Epub 2016 Sep 10 doi: 10.1016/j.fertnstert.2016.08.029. PMID: 27624952
Bhaskar S, Sudhakaran PR, Helen A
Cell Immunol 2016 Dec;310:131-140. Epub 2016 Aug 26 doi: 10.1016/j.cellimm.2016.08.011. PMID: 27585526
Eichhorn T, Rauscher S, Hammer C, Gröger M, Fischer MB, Weber V
Inflammation 2016 Oct;39(5):1737-46. doi: 10.1007/s10753-016-0408-1. PMID: 27503310Free PMC Article
Tsoumani ME, Tatsidou PT, Ntalas IV, Goudevenos JA, Tselepis AD
Platelets 2016 Dec;27(8):812-820. Epub 2016 Jun 23 doi: 10.1080/09537104.2016.1192113. PMID: 27337147

Prognosis

Foy M, Anézo O, Saule S, Planque N
Exp Cell Res 2017 Apr 15;353(2):88-99. Epub 2017 Mar 8 doi: 10.1016/j.yexcr.2017.03.012. PMID: 28284838
Zhao C, Wang A, Lu F, Chen H, Fu P, Zhao X, Chen H
Tumour Biol 2017 Feb;39(2):1010428317691000. doi: 10.1177/1010428317691000. PMID: 28231727
Iwasa M, Miura Y, Fujishiro A, Fujii S, Sugino N, Yoshioka S, Yokota A, Hishita T, Hirai H, Andoh A, Ichinohe T, Maekawa T
Int J Hematol 2017 May;105(5):587-597. Epub 2017 Jan 2 doi: 10.1007/s12185-016-2169-x. PMID: 28044259
Samatov TR, Wicklein D, Tonevitsky AG
Prog Histochem Cytochem 2016 Aug;51(2):25-32. Epub 2016 May 24 doi: 10.1016/j.proghi.2016.05.001. PMID: 27267927
Bapu D, Runions J, Kadhim M, Brooks SA
Cancer Lett 2016 Jun 1;375(2):367-74. Epub 2016 Mar 16 doi: 10.1016/j.canlet.2016.03.019. PMID: 26994652

Clinical prediction guides

Foy M, Anézo O, Saule S, Planque N
Exp Cell Res 2017 Apr 15;353(2):88-99. Epub 2017 Mar 8 doi: 10.1016/j.yexcr.2017.03.012. PMID: 28284838
Qian Y, Shao M, Zou W, Wang L, Cheng R, Hu T
Hum Cell 2017 Apr;30(2):98-105. Epub 2017 Feb 25 doi: 10.1007/s13577-017-0159-9. PMID: 28238196
Zhao C, Wang A, Lu F, Chen H, Fu P, Zhao X, Chen H
Tumour Biol 2017 Feb;39(2):1010428317691000. doi: 10.1177/1010428317691000. PMID: 28231727
Reichert Faria A, Jung JE, Silva de Castro CC, de Noronha L
Pathol Res Pract 2017 Mar;213(3):199-204. Epub 2016 Dec 30 doi: 10.1016/j.prp.2016.12.019. PMID: 28214208
Mobasseri R, Tian L, Soleimani M, Ramakrishna S, Naderi-Manesh H
Biochem Biophys Res Commun 2017 Jan 29;483(1):312-317. Epub 2016 Dec 23 doi: 10.1016/j.bbrc.2016.12.146. PMID: 28025144

Recent systematic reviews

Camacho M, Noller MW, Zaghi S, Reckley LK, Fernandez-Salvador C, Ho E, Dunn B, Chan DK
J Laryngol Otol 2017 May;131(5):378-383. Epub 2017 Feb 14 doi: 10.1017/S0022215117000056. PMID: 28193305
Park S, Kim J, Yoon SH
J Nanosci Nanotechnol 2016 May;16(5):4256-73. PMID: 27483746
Healy MW, Schexnayder B, Connell MT, Terry N, DeCherney AH, Csokmay JM, Yauger BJ, Hill MJ
Am J Obstet Gynecol 2016 Sep;215(3):267-275.e7. Epub 2016 May 10 doi: 10.1016/j.ajog.2016.05.001. PMID: 27173082
Bosteels J, Weyers S, Kasius J, Broekmans FJ, Mol BW, D'Hooghe TM
Cochrane Database Syst Rev 2015 Nov 9;(11):CD011110. doi: 10.1002/14651858.CD011110.pub2. PMID: 26559098
Ahmad G, O'Flynn H, Hindocha A, Watson A
Cochrane Database Syst Rev 2015 Apr 30;(4):CD000475. doi: 10.1002/14651858.CD000475.pub3. PMID: 25924805

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