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Items: 1 to 20 of 34

1.

Estrogenic preparation

A class of natural or synthetic hormones that binds to a cytoplasmic receptor and initiates translocation of the hormone-receptor complex to the nucleus of target cells of tissues rich in estrogen receptors, including the endometrium, myometrium, oviduct, vagina, fallopian tube, cervix, brain, liver, placenta, ovarian cells, Leydigs cells, kidney, prostate, pancreas, heart, and skin. (NCI) [from NCI]

MedGen UID:
8701
Concept ID:
C0014939
Hormone; Organic Chemical; Pharmacologic Substance
2.

Progesterone

A synthetic form of the endogenous hormone progesterone. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy. (NCI04) [from NCI]

MedGen UID:
18661
Concept ID:
C0033308
Hormone; Organic Chemical; Pharmacologic Substance
3.

Increased body weight

An increase in total body weight. [from NCI]

MedGen UID:
12145
Concept ID:
C0043094
Finding
4.

Estradiol

A steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Typically esterified, estradiol derivatives are formulated for oral or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. [from NCI]

MedGen UID:
4551
Concept ID:
C0014912
Hormone; Organic Chemical; Pharmacologic Substance
5.

Weight gain

MedGen UID:
881038
Concept ID:
CN236654
Disease or Syndrome
6.

Agonist

An agent that has affinity for a receptor and intrinsic activity at that receptor. [from NCI]

MedGen UID:
459858
Concept ID:
C2987634
Pharmacologic Substance
7.

Triggered by

Something that sets into motion some course of events; a device that activates or releases or causes something to happen. [from NCI]

MedGen UID:
252950
Concept ID:
C1444748
Qualitative Concept
8.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
9.

Estrogenic Steroids, Alkylated

Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties. [from MeSH]

MedGen UID:
263432
Concept ID:
C1257791
Hormone; Organic Chemical; Pharmacologic Substance
10.

Estinyl

MedGen UID:
195878
Concept ID:
C0699362
Hormone; Organic Chemical; Pharmacologic Substance
11.

Lynoral

MedGen UID:
146998
Concept ID:
C0699367
Hormone; Organic Chemical; Pharmacologic Substance
12.

Phenol

An antiseptic and disinfectant aromatic alcohol. [from MeSH]

MedGen UID:
74524
Concept ID:
C0070570
Organic Chemical; Pharmacologic Substance
13.

Pyrazole Compound

A class of heterocyclic organic compounds characterized by a ring structure composed of three carbon atoms and two nitrogen atoms in adjacent positions. Derivatives of pyrazole exhibit a variety of pharmacological properties, including anti-inflammatory, anti-psychotic, antibiotic and antineoplastic. [from NCI]

MedGen UID:
48274
Concept ID:
C0034242
Organic Chemical; Pharmacologic Substance
14.

Phenol and derivatives

Benzene derivatives that include one or more hydroxyl groups attached to the ring structure. [from MeSH]

MedGen UID:
45854
Concept ID:
C0031428
Organic Chemical; Pharmacologic Substance
15.

Microfollin

MedGen UID:
44427
Concept ID:
C0025985
Organic Chemical; Pharmacologic Substance
16.

Ethinyl Estradiol

A semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in ORAL CONTRACEPTIVES. [from MeSH]

MedGen UID:
41887
Concept ID:
C0015011
Hormone; Organic Chemical; Pharmacologic Substance
17.

Clinical finding

Clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient. [from MeSH]

MedGen UID:
19974
Concept ID:
C0037088
Sign or Symptom
18.

Sex hormone

A class of steroid hormones that specifically binds to and activates androgen, progesterone or estrogen receptors. Sex steroids activate various signaling pathways involved in the development and maintenance of secondary sexual characteristics, reproductive processes, blood salt balance, response to stress, neuronal function and a number of metabolic processes. [from NCI]

MedGen UID:
19951
Concept ID:
C0036884
Hormone; Pharmacologic Substance
19.

Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. [from MeSH]

MedGen UID:
6887
Concept ID:
C0019934
Pharmacologic Substance
20.

Estrogens, Synthetic

Compounds obtained by chemical synthesis which possess estrogenic activity, but differ in structure from naturally occurring estrogens. [from MeSH]

MedGen UID:
4558
Concept ID:
C0014941
Organic Chemical; Pharmacologic Substance
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