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1.

Histiocytoma

MedGen UID:
267592
Concept ID:
C1509147
Neoplastic Process
2.

Cutaneous Fibrous Histiocytoma

A solitary, slowly growing, nodular mass, most often affecting the extremities. It is composed of fibrous and histiocytic cells which infiltrate the dermis and occasionally the underlying subcutaneous tissue. Usually local excision is curative. Recurrences are reported only in a small minority of cases. [from NCI]

MedGen UID:
1930
Concept ID:
C0002991
Neoplastic Process
3.

Misdiagnosis

Incorrect conclusion as to source or cause of illness. [from MeSH]

MedGen UID:
146837
Concept ID:
C0679838
Finding
4.

Dermatofibrosarcomas

A sarcoma of the deep layers of the skin. The tumors are locally aggressive tends to recur but rarely metastatic. It can be classified into variants depending on the cell type tumors are derived from or by its characteristics: Pigmented variant from MELANIN-containing DERMAL DENDRITIC CELLS; Myxoid variant, myxoid STROMAL CELLS; Giant cell variant characterized by GIANT CELLS in the tumors; and Fibrosarcomatous variant chracterized by tumor areas histologically indistinguishable from FIBROSARCOMA. [from MeSH]

MedGen UID:
104907
Concept ID:
C0206647
Neoplastic Process
5.

Methylation

The covalent chemical or biochemical addition of a methyl group(s) to a compound. (NCI) [from NCI]

MedGen UID:
44400
Concept ID:
C0025723
Molecular Function
6.

Giant Cell Fibroblastoma

A rare, locally aggressive fibroblastic neoplasm typically affecting young patients (predominantly boys). It manifests with painless nodules in the dermis or subcutaneous tissues. Morphologically, it contains giant cells and wide vessel-like spaces. This tumor can recur but metastases have not been reported. [from NCI]

MedGen UID:
811326
Concept ID:
C3693482
Neoplastic Process
7.

Dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive, but rarely metastasizing tumor of the deep dermis and subcutaneous tissue. It typically presents during early or middle adult life and is most frequently located on the trunk and proximal extremities (Sandberg et al., 2003). [from OMIM]

MedGen UID:
95938
Concept ID:
C0392784
Neoplastic Process
8.

Heterogeneous

The presence of apparently similar characters for which the genetic evidence indicates that different genes or different genetic mechanisms are involved in different pedigrees. In clinical settings genetic heterogeneity refers to the presence of a variety of genetic defects which cause the same disease, often due to mutations at different loci on the same gene, a finding common to many human diseases including ALZHEIMER DISEASE; CYSTIC FIBROSIS; LIPOPROTEIN LIPASE DEFICIENCY, FAMILIAL; and POLYCYSTIC KIDNEY DISEASES. (Rieger, et al., Glossary of Genetics: Classical and Molecular, 5th ed; Segen, Dictionary of Modern Medicine, 1992) [from MeSH]

MedGen UID:
67020
Concept ID:
C0242960
Organism Attribute
9.

Lesion

A localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part. [from NCI]

MedGen UID:
65128
Concept ID:
C0221198
Finding
10.

Androgenic preparation

A synthetic or animal-derived hormone that is chemically or functionally similar or identical to endogenous androgen with potential use in therapeutic applications. [from NCI]

MedGen UID:
8060
Concept ID:
C0002844
Hormone; Pharmacologic Substance
11.

Connective and Soft Tissue Neoplasm

A benign, intermediate, or malignant neoplasm that affects the connective and soft tissue. [from NCI]

MedGen UID:
60224
Concept ID:
C0206765
Neoplastic Process
12.

Benign Fibrous Histiocytoma

A benign neoplasm composed of fibroblastic spindle cells in a whorled storiform pattern. It is characterized by the presence of foam cells, inflammatory cells, hemosiderin deposition and stromal hemorrhage. [from NCI]

MedGen UID:
60199
Concept ID:
C0206644
Neoplastic Process
13.

Fibrous tissue neoplasm

MedGen UID:
60198
Concept ID:
C0206643
Neoplastic Process
14.

Skin and Connective Tissue Diseases

A collective term for diseases of the skin and its appendages and of connective tissue. [from MeSH]

MedGen UID:
59786
Concept ID:
C0175166
Disease or Syndrome
15.

Neoplasm of connective tissues

Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue. [from MeSH]

MedGen UID:
45035
Concept ID:
C0027656
Neoplastic Process
16.

Disorder of skin

A disorder involving lesions or eruptions of the skin, usually without inflammation. [from NCI]

MedGen UID:
20777
Concept ID:
C0037274
Disease or Syndrome
17.

Neoplasm of the skin

A tumor (abnormal growth of tissue) of the skin. [from HPO]

MedGen UID:
19993
Concept ID:
C0037286
Neoplastic Process
18.

Pigmented Dermatofibrosarcoma Protuberans

A morphologic variant of dermatofibrosarcoma protuberans characterized by the presence of melanin-pigmented dendritic cells. [from NCI]

MedGen UID:
90786
Concept ID:
C0334464
Neoplastic Process
19.

Myxoid Dermatofibrosarcoma Protuberans

A morphologic variant of dermatofibrosarcoma protuberans characterized by the presence of extensive myxoid stroma formation and a storiform growth pattern. [from NCI]

MedGen UID:
90785
Concept ID:
C0334454
Neoplastic Process
20.

Dermatofibrosarcoma protuberans with giant cell fibroblastoma

MedGen UID:
698534
Concept ID:
C1275251
Neoplastic Process
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