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Solitary rectal ulcer syndrome

MedGen UID:
798620
Concept ID:
CN200964
Disease or Syndrome
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
 
Orphanet: ORPHA209964

Definition

Solitary rectal ulcer syndrome (SRUS) is a rare rectal disease characterized by rectal bleeding, abdominal pain, passage of mucus, sensation of incomplete evacuation, straining at defecation and rectal prolapsed, secondary to ischemic changes in the rectum. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSolitary rectal ulcer syndrome
Follow this link to review classifications for Solitary rectal ulcer syndrome in Orphanet.

Recent clinical studies

Etiology

Behera MK, Dixit VK, Shukla SK, Ghosh JK, Abhilash VB, Asati PK, Jain AK
Trop Gastroenterol 2015 Oct-Dec;36(4):244-50. PMID: 27509702
Evans C, Ong E, Jones OM, Cunningham C, Lindsey I
Colorectal Dis 2014 Mar;16(3):O112-6. PMID: 24678526
Abid S, Khawaja A, Bhimani SA, Ahmad Z, Hamid S, Jafri W
BMC Gastroenterol 2012 Jun 14;12:72. doi: 10.1186/1471-230X-12-72. PMID: 22697798Free PMC Article
Blackburn C, McDermott M, Bourke B
J Pediatr Gastroenterol Nutr 2012 Feb;54(2):263-5. doi: 10.1097/MPG.0b013e31823014c0. PMID: 22266488
Choi HJ, Shin EJ, Hwang YH, Weiss EG, Nogueras JJ, Wexner SD
Surg Innov 2005 Dec;12(4):307-13. PMID: 16424950

Diagnosis

Behera MK, Dixit VK, Shukla SK, Ghosh JK, Abhilash VB, Asati PK, Jain AK
Trop Gastroenterol 2015 Oct-Dec;36(4):244-50. PMID: 27509702
Abbasi A, Bhutto AR, Taj A, Aurangzaib, Baloch A, Masroor M, Munir SM
J Coll Physicians Surg Pak 2015 Dec;25(12):867-9. doi: 12.2015/JCPSP.867869. PMID: 26691359
Evans C, Ong E, Jones OM, Cunningham C, Lindsey I
Colorectal Dis 2014 Mar;16(3):O112-6. PMID: 24678526
Zhu QC, Shen RR, Qin HL, Wang Y
World J Gastroenterol 2014 Jan 21;20(3):738-44. doi: 10.3748/wjg.v20.i3.738. PMID: 24574747Free PMC Article
Dehghani SM, Malekpour A, Haghighat M
World J Gastroenterol 2012 Dec 7;18(45):6541-5. doi: 10.3748/wjg.v18.i45.6541. PMID: 23236227Free PMC Article

Therapy

Abbasi A, Bhutto AR, Taj A, Aurangzaib, Baloch A, Masroor M, Munir SM
J Coll Physicians Surg Pak 2015 Dec;25(12):867-9. doi: 12.2015/JCPSP.867869. PMID: 26691359
Urgancı N, Kalyoncu D, Eken KG
Gut Liver 2013 Nov;7(6):752-5. Epub 2013 Nov 11 doi: 10.5009/gnl.2013.7.6.752. PMID: 24312719Free PMC Article
Perito ER, Mileti E, Dalal DH, Cho SJ, Ferrell LD, McCracken M, Heyman MB
J Pediatr Gastroenterol Nutr 2012 Feb;54(2):266-70. doi: 10.1097/MPG.0b013e318240bba5. PMID: 22094902Free PMC Article
Bulut T, Canbay E, Yamaner S, Gulluoglu M, Bugra D
Int Surg 2011 Jan-Mar;96(1):45-50. PMID: 21675619
Sood SK, Garner JP, Amin SN
Dis Colon Rectum 2008 Jul;51(7):1149-52. Epub 2008 Apr 5 doi: 10.1007/s10350-008-9268-6. PMID: 18392597

Prognosis

Blackburn C, McDermott M, Bourke B
J Pediatr Gastroenterol Nutr 2012 Feb;54(2):263-5. doi: 10.1097/MPG.0b013e31823014c0. PMID: 22266488
Perito ER, Mileti E, Dalal DH, Cho SJ, Ferrell LD, McCracken M, Heyman MB
J Pediatr Gastroenterol Nutr 2012 Feb;54(2):266-70. doi: 10.1097/MPG.0b013e318240bba5. PMID: 22094902Free PMC Article
Al-Brahim N, Al-Awadhi N, Al-Enezi S, Alsurayei S, Ahmad M
Saudi J Gastroenterol 2009 Jul-Sep;15(3):188-92. doi: 10.4103/1319-3767.54749. PMID: 19636181Free PMC Article
Ortega AE, Klipfel N, Kelso R, Petrone P, Román I, Díaz A, Avalos B, Kaufman HS
Am Surg 2008 Oct;74(10):967-72. PMID: 18942624
Sood SK, Garner JP, Amin SN
Dis Colon Rectum 2008 Jul;51(7):1149-52. Epub 2008 Apr 5 doi: 10.1007/s10350-008-9268-6. PMID: 18392597

Clinical prediction guides

Abbasi A, Bhutto AR, Taj A, Aurangzaib, Baloch A, Masroor M, Munir SM
J Coll Physicians Surg Pak 2015 Dec;25(12):867-9. doi: 12.2015/JCPSP.867869. PMID: 26691359
Evans C, Ong E, Jones OM, Cunningham C, Lindsey I
Colorectal Dis 2014 Mar;16(3):O112-6. PMID: 24678526
Badrek-Amoudi AH, Roe T, Mabey K, Carter H, Mills A, Dixon AR
Colorectal Dis 2013 May;15(5):575-81. doi: 10.1111/codi.12077. PMID: 23107777
Abid S, Khawaja A, Bhimani SA, Ahmad Z, Hamid S, Jafri W
BMC Gastroenterol 2012 Jun 14;12:72. doi: 10.1186/1471-230X-12-72. PMID: 22697798Free PMC Article
Suresh N, Ganesh R, Sathiyasekaran M
Indian Pediatr 2010 Dec;47(12):1059-61. Epub 2010 Mar 15 PMID: 20453265

Recent systematic reviews

Rao SS, Benninga MA, Bharucha AE, Chiarioni G, Di Lorenzo C, Whitehead WE
Neurogastroenterol Motil 2015 May;27(5):594-609. Epub 2015 Apr 1 doi: 10.1111/nmo.12520. PMID: 25828100Free PMC Article

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