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Ehrlichiosis

MedGen UID:
39039
Concept ID:
C0085399
Disease or Syndrome
Synonyms: Ehrlichia Infection; Ehrlichia Infections; Ehrlichioses; Infection, Ehrlichia; Infections, Ehrlichia
SNOMED CT: Ehrlichiosis (77361002)
 
Orphanet: ORPHA1902

Definition

A tick-borne disease characterized by FEVER; HEADACHE; myalgias; ANOREXIA; and occasionally RASH. It is caused by several bacterial species and can produce disease in DOGS; CATTLE; SHEEP; GOATS; HORSES; and humans. The primary species causing human disease are EHRLICHIA CHAFFEENSIS; ANAPLASMA PHAGOCYTOPHILUM; and Ehrlichia ewingii. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEhrlichiosis
Follow this link to review classifications for Ehrlichiosis in Orphanet.

Recent clinical studies

Etiology

Geier C, Davis J, Siegel M
BMJ Case Rep 2016 Oct 6;2016 doi: 10.1136/bcr-2016-215967. PMID: 27758794
Nichols Heitman K, Dahlgren FS, Drexler NA, Massung RF, Behravesh CB
Am J Trop Med Hyg 2016 Jan;94(1):52-60. Epub 2015 Nov 30 doi: 10.4269/ajtmh.15-0540. PMID: 26621561Free PMC Article
Chattoraj P, Yang Q, Khandai A, Al-Hendy O, Ismail N
PLoS One 2013;8(3):e58514. Epub 2013 Mar 19 doi: 10.1371/journal.pone.0058514. PMID: 23526993Free PMC Article
Folkema AM, Holman RC, Dahlgren FS, Cheek JE, McQuiston JH
Am J Trop Med Hyg 2012 Sep;87(3):529-37. Epub 2012 Jul 23 doi: 10.4269/ajtmh.2012.12-0060. PMID: 22826495Free PMC Article
Lawrence KL, Morrell MR, Storch GA, Hachem RR, Trulock EP
Transpl Infect Dis 2009 Jun;11(3):203-10. Epub 2009 Feb 18 doi: 10.1111/j.1399-3062.2009.00373.x. PMID: 19228344

Diagnosis

Ismail N, McBride JW
Clin Lab Med 2017 Jun;37(2):317-340. Epub 2017 Mar 25 doi: 10.1016/j.cll.2017.01.006. PMID: 28457353
Kaplan RM, Swat SA, Singer BD
Diagn Microbiol Infect Dis 2016 Nov;86(3):327-328. Epub 2016 Aug 13 doi: 10.1016/j.diagmicrobio.2016.08.007. PMID: 27575459Free PMC Article
Sosa-Gutierrez CG, Solorzano-Santos F, Walker DH, Torres J, Serrano CA, Gordillo-Perez G
Emerg Infect Dis 2016 May;22(5):871-4. doi: 10.3201/eid2205.151217. PMID: 27088220Free PMC Article
Mutneja R, Shah M, Shivamurthy P, Gowani S, Delgado-Colon D, Lawlor M
Conn Med 2014 Jun-Jul;78(6):345-7. PMID: 25672061
Arsić B, Gligić A, Ristanović E, Lako B, Potkonjak A, Perunicić M, Pavlović M
Srp Arh Celok Lek 2014 Jan-Feb;142(1-2):79-82. PMID: 24684037

Therapy

Geier C, Davis J, Siegel M
BMJ Case Rep 2016 Oct 6;2016 doi: 10.1136/bcr-2016-215967. PMID: 27758794
Cheng A, Williams F, Fortenberry J, Preissig C, Salinas S, Kamat P
Pediatrics 2016 Oct;138(4) Epub 2016 Sep 15 doi: 10.1542/peds.2015-4176. PMID: 27633921
Sosa-Gutierrez CG, Solorzano-Santos F, Walker DH, Torres J, Serrano CA, Gordillo-Perez G
Emerg Infect Dis 2016 May;22(5):871-4. doi: 10.3201/eid2205.151217. PMID: 27088220Free PMC Article
Mutneja R, Shah M, Shivamurthy P, Gowani S, Delgado-Colon D, Lawlor M
Conn Med 2014 Jun-Jul;78(6):345-7. PMID: 25672061
Arsić B, Gligić A, Ristanović E, Lako B, Potkonjak A, Perunicić M, Pavlović M
Srp Arh Celok Lek 2014 Jan-Feb;142(1-2):79-82. PMID: 24684037

Prognosis

Geier C, Davis J, Siegel M
BMJ Case Rep 2016 Oct 6;2016 doi: 10.1136/bcr-2016-215967. PMID: 27758794
Sosa-Gutierrez CG, Solorzano-Santos F, Walker DH, Torres J, Serrano CA, Gordillo-Perez G
Emerg Infect Dis 2016 May;22(5):871-4. doi: 10.3201/eid2205.151217. PMID: 27088220Free PMC Article
Dahlgren FS, Heitman KN, Behravesh CB
Am J Trop Med Hyg 2016 Feb;94(2):299-301. Epub 2015 Nov 30 doi: 10.4269/ajtmh.15-0691. PMID: 26621564Free PMC Article
Saito TB, Thirumalapura NR, Shelite TR, Rockx-Brouwer D, Popov VL, Walker DH
J Infect Dis 2015 Feb 1;211(3):452-61. Epub 2014 Jul 2 doi: 10.1093/infdis/jiu372. PMID: 24990203Free PMC Article
Folkema AM, Holman RC, Dahlgren FS, Cheek JE, McQuiston JH
Am J Trop Med Hyg 2012 Sep;87(3):529-37. Epub 2012 Jul 23 doi: 10.4269/ajtmh.2012.12-0060. PMID: 22826495Free PMC Article

Clinical prediction guides

Raghavan RK, Neises D, Goodin DG, Andresen DA, Ganta RR
PLoS One 2014;9(7):e100850. Epub 2014 Jul 3 doi: 10.1371/journal.pone.0100850. PMID: 24992684Free PMC Article
Ismail N, Walker DH, Ghose P, Tang YW
BMC Immunol 2012 May 21;13:26. doi: 10.1186/1471-2172-13-26. PMID: 22607204Free PMC Article
MacNamara KC, Racine R, Chatterjee M, Borjesson D, Winslow GM
Infect Immun 2009 Sep;77(9):4061-9. Epub 2009 May 18 doi: 10.1128/IAI.01550-08. PMID: 19451243Free PMC Article
Dierberg KL, Dumler JS
BMC Infect Dis 2006 Jul 21;6:121. doi: 000294863. PMID: 16859547Free PMC Article
Ismail N, Walker DH
Ann N Y Acad Sci 2005 Dec;1063:383-94. doi: 10.1196/annals.1355.070. PMID: 16481546

Recent systematic reviews

Biggs HM, Behravesh CB, Bradley KK, Dahlgren FS, Drexler NA, Dumler JS, Folk SM, Kato CY, Lash RR, Levin ML, Massung RF, Nadelman RB, Nicholson WL, Paddock CD, Pritt BS, Traeger MS
MMWR Recomm Rep 2016 May 13;65(2):1-44. doi: 10.15585/mmwr.rr6502a1. PMID: 27172113
Nieto NC, Foley JE
Vector Borne Zoonotic Dis 2009 Feb;9(1):93-102. Epub 2008 Sep 15 doi: 10.1089/vbz.2008.0072. PMID: 18789001
Chapman AS, Bakken JS, Folk SM, Paddock CD, Bloch KC, Krusell A, Sexton DJ, Buckingham SC, Marshall GS, Storch GA, Dasch GA, McQuiston JH, Swerdlow DL, Dumler SJ, Nicholson WL, Walker DH, Eremeeva ME, Ohl CA; Tickborne Rickettsial Diseases Working Group.; CDC.
MMWR Recomm Rep 2006 Mar 31;55(RR-4):1-27. PMID: 16572105
Donovan BJ, Weber DJ, Rublein JC, Raasch RH
Ann Pharmacother 2002 Oct;36(10):1590-7. doi: 10.1345/aph.1C089. PMID: 12243610
Jantausch BA
Ann Allergy 1994 Jul;73(1):4-11; quiz 11-2. PMID: 8030801

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