Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 19

1.

Opiate agonist

A class of synthetic chemicals/drugs similar to opiates (opium derivatives) with analgesic properties. Due to binding to opiate receptors, opioids mimic opiate activity on neurons, various cells (i.e. lymphocytes), pain suppression and other neurobehavioral activity. (NCI) [from NCI]

MedGen UID:
66892
Concept ID:
C0242402
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
2.

Corticotropin-Releasing Hormone

A hormone synthesized in the hypothalamus and regulates the secretion of adrenocorticotropic hormone (ACTH). [from NCI]

MedGen UID:
3632
Concept ID:
C0010132
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
3.

corticotropin, human

A hormone made in the pituitary gland. ACTH acts on the outer part of the adrenal gland to control its release of corticosteroid hormones. More ACTH is made during times of stress. [from NCI_NCI-GLOSS]

MedGen UID:
896260
Concept ID:
C3818725
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
4.

Multiple endocrine neoplasia

An autosomal dominant inherited neoplastic syndrome characterized by the development of various endocrine neoplasms and abnormalities in various anatomic sites. There are three types recognized: type 1 (MEN 1), caused by inactivation of the tumor suppressor gene MEN-1, type 2A (MEN 2A), caused by mutation of the RET gene, and type 2B (MEN 2B) also caused by mutation of the RET gene. Patients with MEN 1 may develop hyperparathyroidism and parathyroid gland adenomas, pituitary gland adenomas, pancreatic islet cell neoplasms, and carcinoid tumors. Patients with MEN 2A develop medullary thyroid carcinomas, and may also develop pheochromocytomas and parathyroid gland hyperplasia. Patients with MEN 2B develop medullary thyroid carcinomas and numerous neural defects including neuromas. [from NCI]

MedGen UID:
45036
Concept ID:
C0027662
Neoplastic Process
5.

Hydrocortisone

The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. [from MeSH]

MedGen UID:
9337
Concept ID:
C0020268
Hormone; Organic Chemical; Pharmacologic Substance
6.

Naloxon-ratiopharm

MedGen UID:
260630
Concept ID:
C1449884
Organic Chemical; Pharmacologic Substance
7.

Nalone

MedGen UID:
258584
Concept ID:
C1449882
Organic Chemical; Pharmacologic Substance
8.

MRZ-2593

MedGen UID:
149072
Concept ID:
C0729156
Organic Chemical; Pharmacologic Substance
9.

Narcan

MedGen UID:
146883
Concept ID:
C0684237
Organic Chemical; Pharmacologic Substance
10.

Sensory System Agents

Drugs that act on neuronal sensory receptors resulting in an increase, decrease, or modification of afferent nerve activity. (From Smith and Reynard, Textbook of Pharmacology, 1991, p367) [from MeSH]

MedGen UID:
67054
Concept ID:
C0243058
Pharmacologic Substance
11.

Peripheral Nervous System Agents

Drugs that act principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. (From Smith and Reynard, Textbook of Pharmacology, 1991, p75) [from MeSH]

MedGen UID:
67048
Concept ID:
C0243049
Pharmacologic Substance
12.

Opiate Alkaloids

broad family of plant alkaloids with narcotic effects; historically used as sedatives, anesthetics, analgesics, and euphoriants; heroin and morphine are highly addictive, abused drugs. [from CRISP]

MedGen UID:
66385
Concept ID:
C0221793
Organic Chemical; Pharmacologic Substance
13.

protein folding

Processes involved in the formation of TERTIARY PROTEIN STRUCTURE. [from MeSH]

MedGen UID:
58195
Concept ID:
C0162847
Molecular Function
14.

Protein denaturation

Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein. [from MeSH]

MedGen UID:
10970
Concept ID:
C0033627
Molecular Function
15.

Phenanthrenes

MedGen UID:
10693
Concept ID:
C0031368
Organic Chemical; Pharmacologic Substance
16.

Alkaloid

organic nitrogenous bases; many alkaloids of medical importance occur in the animal and vegetable kingdoms. [from CRISP]

MedGen UID:
7968
Concept ID:
C0002062
Organic Chemical; Pharmacologic Substance
17.

Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. [from MeSH]

MedGen UID:
6887
Concept ID:
C0019934
Pharmacologic Substance
18.

Narcotic Antagonists

Any agent that binds to or interferes with binding to any of the opioid receptor subtypes, thereby blocking the actions of opioid agonists. [from NCI]

MedGen UID:
6521
Concept ID:
C0027410
Pharmacologic Substance
19.

Central Nervous System Agents

A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252) [from MeSH]

MedGen UID:
836
Concept ID:
C0007680
Pharmacologic Substance
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center