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Items: 1 to 20 of 28

1.

Thrombin

An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN. [from MeSH]

MedGen UID:
11796
Concept ID:
C0040018
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
2.

Bovine thrombin

MedGen UID:
452981
Concept ID:
C1337342
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
3.

AT 10

MedGen UID:
108470
Concept ID:
C0591126
Organic Chemical; Pharmacologic Substance
4.

Coagulation factor II

A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia. [from MeSH]

MedGen UID:
19527
Concept ID:
C0033706
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
5.

Posterior cortical atrophy

Posterior Cortical Atrophy (PCA) is a rare progressive neurodegenerative disorder with a typical onset between 50-65 years of age characterized by progressive impairment of higher visual processing skills and other posterior cortical functions without any evidence of ocular abnormalities. [from ORDO]

MedGen UID:
799015
Concept ID:
CN205270
Disease or Syndrome
6.

Prothrombin

MedGen UID:
417935
Concept ID:
C2828369
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
7.

Choanal atresia, posterior

Absence or abnormal closure of the posterior portion of the choana (the posterior nasal aperture). [from HPO]

MedGen UID:
66321
Concept ID:
C0220723
Finding; Finding
8.

Thrombostat

MedGen UID:
196178
Concept ID:
C0702033
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
9.

Inborn genetic diseases

Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations may be inherited from a parent's genome or they may be acquired in utero. [from MeSH]

MedGen UID:
181981
Concept ID:
C0950123
Disease or Syndrome
10.

Blood Coagulation Disorders, Inherited

Hemorrhagic and thrombotic disorders that occur as a consequence of inherited abnormalities in blood coagulation. [from MeSH]

MedGen UID:
163105
Concept ID:
C0852077
Disease or Syndrome
11.

Thrombinar

MedGen UID:
152360
Concept ID:
C0702032
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
12.

Glanzmann thrombasthenia

Glanzmann thrombasthenia is an autosomal recessive bleeding disorder characterized by failure of platelet aggregation and by absent or diminished clot retraction. The abnormalities are related to quantitative or qualitative abnormalities of the GPIIb/IIIa platelet surface fibrinogen receptor complex resulting from mutations in either the GPIIb or GPIIIa genes (Rosenberg et al., 1997). See 187800 for discussion of a possible dominant form. [from GTR]

MedGen UID:
52736
Concept ID:
C0040015
Disease or Syndrome
13.

Protease preparation

A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule. [from NCI]

MedGen UID:
45389
Concept ID:
C0030946
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
14.

Intracellular Second Messenger

A non-proteinaceous signaling molecule that is generated by intracellular enzymes that respond to the binding of extracellular ligands to cell surface receptors. These compounds serve as intermediate signals for a diverse set of cellular processes. [from NCI]

MedGen UID:
19914
Concept ID:
C0036522
Molecular Function
15.

beta,gamma-Thrombin

MedGen UID:
14084
Concept ID:
C0005177
Amino Acid, Peptide, or Protein; Pharmacologic Substance
16.

gamma-Thrombin

MedGen UID:
8955
Concept ID:
C0017052
Amino Acid, Peptide, or Protein; Pharmacologic Substance
17.

Haemorrhagic disorders

Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (BLOOD COAGULATION DISORDERS) or another abnormality causing a structural flaw in the blood vessels (HEMOSTATIC DISORDERS). [from MeSH]

MedGen UID:
6799
Concept ID:
C0019087
Disease or Syndrome
18.

Hemic and Lymphatic Diseases

Hematologic diseases and diseases of the lymphatic system collectively. Hemic diseases include disorders involving the formed elements (e.g., ERYTHROCYTE AGGREGATION, INTRAVASCULAR) and chemical components (e.g., BLOOD PROTEIN DISORDERS); lymphatic diseases include disorders relating to lymph, lymph nodes, and lymphocytes. [from MeSH]

MedGen UID:
6780
Concept ID:
C0018981
Disease or Syndrome
19.

Hematologic disease

An abnormality of the hematopoietic system. [from HPO]

MedGen UID:
5483
Concept ID:
C0018939
Disease or Syndrome
20.

beta-Thrombin

MedGen UID:
2612
Concept ID:
C0005285
Amino Acid, Peptide, or Protein; Pharmacologic Substance
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