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Items: 10

1.

agonists

Used with chemicals, drugs, and endogenous substances to indicate substances or agents that have affinity for a receptor and intrinsic activity at that receptor. (From Textbook of Pharmacology, 1991, p.16) [from MeSH]

MedGen UID:
116746
Concept ID:
C0243192
Pharmacologic Substance
2.

Ipratropium

A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic. [from MeSH]

MedGen UID:
10164
Concept ID:
C0027235
Organic Chemical; Pharmacologic Substance
3.

Chronic obstructive pulmonary disease

MedGen UID:
505916
Concept ID:
CN005670
Finding
4.

Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a common, complex disorder associated with substantial morbidity and mortality. COPD is defined by irreversible airflow obstruction due to chronic bronchitis, emphysema, and/or small airways disease. Airflow obstruction is typically determined by reductions in quantitative spirometric indices, including forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) (Silverman et al., 2002; Celedon et al., 2004). [from OMIM]

MedGen UID:
9818
Concept ID:
C0024117
Disease or Syndrome
5.

Itrop

MedGen UID:
147137
Concept ID:
C0700650
Organic Chemical; Pharmacologic Substance
6.

Atrovent

MedGen UID:
108471
Concept ID:
C0591130
Organic Chemical; Pharmacologic Substance
7.

Sch-1178

MedGen UID:
57903
Concept ID:
C0162426
Organic Chemical; Pharmacologic Substance
8.

Sch-1000

MedGen UID:
9552
Concept ID:
C0022055
Organic Chemical; Pharmacologic Substance
9.

pirbuterol

A short-acting, beta-adrenergic receptor agonist with bronchodilator activity. Pirbuterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells. [from NCI]

MedGen UID:
20230
Concept ID:
C0071129
Organic Chemical; Pharmacologic Substance
10.

Isoetharine

Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma. [from MeSH]

MedGen UID:
5907
Concept ID:
C0022176
Organic Chemical; Pharmacologic Substance
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