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Items: 2

1.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
2.

pyroxamide

A synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy. (NCI04) [from NCI]

MedGen UID:
196845
Concept ID:
C0966748
Organic Chemical; Pharmacologic Substance

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